青少年复发性呼吸道乳头状瘤病：2024 年我们将知道什么？

IF 4.7 Q1 VIROLOGY Tumour Virus Research Pub Date : 2024-04-27 DOI:10.1016/j.tvr.2024.200281

Charles Lepine , Nicolas Leboulanger , Cécile Badoual

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摘要

幼年复发性呼吸道乳头状瘤病是一种终身性良性鳞状病变，与人乳头状瘤病毒感染有关，尤其是人乳头状瘤病毒 6 和人乳头状瘤病毒 11 基因型。这种病变很少见，但可导致喉闭塞，引起致残性呼吸困难，或转化为鳞状细胞癌。本文旨在从流行病学、生物学和临床角度概述这种病变，尤其是儿童病变，以便了解在研究和开发医疗及治疗管理工具方面存在的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Juvenile onset recurrent respiratory papillomatosis: What do we know in 2024 ?

Juvenile onset recurrent respiratory papillomatosis is a lifelong benign squamous lesion associated with HPV infection, particularly HPV6 and HPV11 genotypes. These lesions are rare, but can lead to laryngeal obturations, which can cause disabling dyspnea, or transform into squamous cell carcinoma. The aim here is to provide an epidemiological, biological and clinical overview of this pathology, particularly in children, in order to understand the issues at stake in terms of research and the development of medical and therapeutic management tools.

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