头颈部癌症放疗后吞咽困难:言语病理学家的当前处理方法

IF 3.8 2区 医学 Q2 ONCOLOGY Current Treatment Options in Oncology Pub Date : 2024-05-01 DOI:10.1007/s11864-024-01198-0
Roganie Govender, Nicky Gilbody, Gavriella Simson, Rhiannon Haag, Ceri Robertson, Emma Stuart
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引用次数: 0

摘要

吞咽困难(进食和饮水困难)仍然是头颈部癌症(HNC)放疗最常见的副作用,对患者的功能和生活质量(QOL)造成严重影响。在过去的十年中,由于治疗方法的进步、吸烟人数的减少、人乳头瘤病毒(HPV)疫苗的引入以及 HPV 相关癌症预后的改善等多种因素,5 年生存率有所提高。人乳头瘤病毒阳性疾病的发病率增加,往往会影响到年轻人,这导致癌症后遗症和治疗后遗症患者的寿命延长。放疗的晚期影响可能会导致一些长期存活者的吞咽困难恶化,或导致其他患者新发吞咽困难,从而加重症状。语言病理学(SLP)的投入仍然是评估和处理 HNC 治疗后吞咽困难的核心。在本文中,我们将介绍目前针对放疗后吞咽困难的语言病理治疗。我们讨论了传统治疗方法、辅助治疗方法的出现以及当前的服务提供模式。文中还强调了坚持治疗对治疗效果的影响。尽管治疗方法不断进步,但患者仍会出现吞咽困难,对现有的干预方法产生抵触情绪。治疗方案千差万别,而支持最佳治疗类型、时间和强度的证据却十分匮乏。我们讨论了进一步研究的必要性,包括探讨放疗对中枢神经系统(CNS)的影响、肌肉疏松症与放疗引起的吞咽困难之间的联系以及视觉生物反馈在康复中的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Post-Radiotherapy Dysphagia in Head and Neck Cancer: Current Management by Speech-Language Pathologists

Dysphagia, difficulty in eating and drinking, remains the most common side effect of radiotherapy treatment for head and neck cancer (HNC) with devastating consequences for function and quality of life (QOL). Over the past decade, 5-year survival has improved due to multiple factors including treatment advances, reduction in smoking, introduction of the human papillomavirus (HPV) vaccine and more favourable prognosis of HPV-related cancers. Increased prevalence of HPV-positive disease, which tends to affect younger individuals, has led to an elevated number of people living for longer with the sequelae of cancer and its treatment. Symptoms are compounded by late effects of radiotherapy which may lead to worsening of dysphagia for some long-term survivors or new-onset dysphagia for others. Speech-language pathology (SLP) input remains core to the assessment and management of dysphagia following HNC treatment. In this article, we present current SLP management of dysphagia post-radiotherapy. We discuss conventional treatment approaches, the emergence of therapy adjuncts and current service delivery models. The impact of adherence on therapy outcomes is highlighted. Despite treatment advancements, patients continue to present with dysphagia which is resistant to existing intervention approaches. There is wide variation in treatment programmes, with a paucity of evidence to support optimal type, timing and intensity of treatment. We discuss the need for further research, including exploration of the impact of radiotherapy on the central nervous system (CNS), the link between sarcopenia and radiotherapy-induced dysphagia and the benefits of visual biofeedback in rehabilitation.

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来源期刊
CiteScore
7.10
自引率
0.00%
发文量
113
审稿时长
>12 weeks
期刊介绍: This journal aims to review the most important, recently published treatment option advances in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to facilitate worldwide approaches to cancer treatment. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endocrine tumors, lymphomas, neuro-oncology, and cancers of the breast, head and neck, lung, skin, gastrointestinal tract, and genitourinary region. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known oncologists, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.
期刊最新文献
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