阴道毛滴虫药物敏感性体外测试:评估与治疗成功率相关的塞克硝唑最小致死浓度

IF 1.7 4区 医学 Q3 INFECTIOUS DISEASES Sexually transmitted diseases Pub Date : 2024-11-01 Epub Date: 2024-04-30 DOI:10.1097/OLQ.0000000000001992
Keonte J Graves, Jan Novak, Hemant K Tiwari, W Evan Secor, Peter Augostini, Christina A Muzny
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引用次数: 0

摘要

摘要:我们测定了塞克硝唑(SEC)的体外最低致死浓度(MLC),并评估了从71名妇女中分离出的阴道球菌与临床药敏性之间的相关性,其中66人成功接受了这种药物的治疗。在这项研究中,MLC ≤12.5 μg/ml 与临床药敏性相关。
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In Vitro Testing of Trichomonas vaginalis Drug Susceptibility: Evaluation of Minimal Lethal Concentration for Secnidazole That Correlates With Treatment Success.

Abstract: We determined the in vitro minimum lethal concentration of secnidazole and assessed the correlation with clinical susceptibility among Trichomonas vaginalis isolates obtained from 71 women, of whom 66 were successfully treated with this medication. A minimum lethal concentration ≤12.5 μg/mL correlated with clinical susceptibility in this study.

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来源期刊
Sexually transmitted diseases
Sexually transmitted diseases 医学-传染病学
CiteScore
4.00
自引率
16.10%
发文量
289
审稿时长
3-8 weeks
期刊介绍: ​Sexually Transmitted Diseases, the official journal of the American Sexually Transmitted Diseases Association​, publishes peer-reviewed, original articles on clinical, laboratory, immunologic, epidemiologic, behavioral, public health, and historical topics pertaining to sexually transmitted diseases and related fields. Reports from the CDC and NIH provide up-to-the-minute information. A highly respected editorial board is composed of prominent scientists who are leaders in this rapidly changing field. Included in each issue are studies and developments from around the world.
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