帕金森病可能临床诊断方法的发展:事件相关电位。

IF 0.6 4区 医学 Q4 CLINICAL NEUROLOGY Neurocase Pub Date : 2023-06-01 Epub Date: 2024-04-27 DOI:10.1080/13554794.2024.2345404
Burcak Yavuz, Emir Rusen, Tugce Duman, Berra Bas
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引用次数: 0

摘要

本研究通过对事件相关电位(ERP)进行分析,来检测接受深部脑刺激(DBS)的帕金森病患者的认知障碍。共有85名志愿者接受了ERP分析和神经心理学测试(NPT),以确定其认知水平。在 ERP 分析中,观察到帕金森病组的潜伏期延长。然而,植入 DBS 的患者的潜伏期缩短,症状减轻,认知和注意力技能均有统计学改善。考虑到所有这些数据,ERP的结果很有希望成为一种无创方法,可用于疾病状态和帕金森病的诊断。
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Developments of possible clinical diagnostic methods for parkinson's disease: event-related potentials.

In this study, Event-Related Potential (ERP) analyzes were performed to detect cognitive impairments in PD with Deep Brain Stimulation (DBS). A total of 85 volunteers underwent ERP analysis and neuropsychological testing (NPT) to determine cognitive level. In ERP analyses, prolonged latencies were observed in PD groups. However, patients implanted with DBS showed a decrease in latencies, a decrease in symptoms and statistical improvements in both cognitive and attention skills. Considering all these data, ERP results are promising as a noninvasive method that can be used in both disease status and diagnosis of PD.

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来源期刊
Neurocase
Neurocase 医学-精神病学
CiteScore
1.40
自引率
12.50%
发文量
70
审稿时长
6-12 weeks
期刊介绍: Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.
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