[年轻患者肺动静脉畸形引起的矛盾性栓塞导致缺血性中风]。

Pub Date : 2024-01-01
Matías J Alet, Hernán Bertoni, Sebastián F Ameriso
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引用次数: 0

摘要

孤立性肺动静脉畸形(PAVM)导致的矛盾性栓塞是缺血性脑卒中的罕见病因。肺动静脉畸形是肺动脉和静脉之间异常的高流量连接,使脱氧血液进入全身循环,是一种不太常见的矛盾性栓塞来源,尤其是在年轻人中。血管内栓塞是治疗有临床意义的 PAVM 的首选方法。我们介绍了一例左侧丘脑缺血性中风的 34 岁女性病例。经颅多普勒检查发现脑动脉有严重的造影剂通过。心内超声检查未发现卵圆孔,因此进一步进行了肺部 CT 血管造影检查,证实了 PAVM 的存在。患者成功接受了血管内治疗。在缺血性脑卒中的病因诊断中考虑 PAVM 至关重要,尤其是对于有右左沟通异常迹象的年轻患者。建议定期进行随访成像,以评估 PAVM 的潜在复发或变化,强调对这些畸形进行适当治疗的重要性。
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[Ischemic stroke due to paradoxical embolism through pulmonary arteriovenous malformation in a young patient].

Paradoxical embolism due to an isolated pulmonary arteriovenous malformation (PAVM) is a rare cause of ischemic stroke. PAVMs are abnormal high-flow connections between pulmonary arteries and veins, diverting deoxygenated blood into the systemic circulation and they represent a less common source of paradoxical embolisms, especially in young individuals. Endovascular embolization is the preferred treatment for clinically significant PAVMs. We present the case of a 34-year-old woman with a left thalamic ischemic stroke. Severe contrast passage was detected in cerebral arteries through transcranial Doppler. Intracardiac ultrasound did not reveal a patent foramen ovale, prompting further investigation with pulmonary CT angiography, confirming the presence of PAVM. The patient underwent successful endovascular treatment. It is essential to consider PAVM in the etiological diagnosis of ischemic stroke, especially in young patients with signs of abnormal right-to-left communication. Periodic follow-up imaging is recommended to assess potential recurrence or changes in PAVM, emphasizing the importance of appropriate management of these malformations.

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