与青少年反社会行为相关的大脑皮层性别二形体积。

Psychoradiology Pub Date : 2023-12-19 eCollection Date: 2023-01-01 DOI:10.1093/psyrad/kkad031
Ke Ding, Miao Xu, Taicheng Huang, Yiying Song, Feng Kong, Zonglei Zhen
{"title":"与青少年反社会行为相关的大脑皮层性别二形体积。","authors":"Ke Ding, Miao Xu, Taicheng Huang, Yiying Song, Feng Kong, Zonglei Zhen","doi":"10.1093/psyrad/kkad031","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Although sex differences in antisocial behavior are well-documented, the extent to which neuroanatomical differences are related to sex differences in antisocial behavior is unclear. The inconsistent results from different clinical populations exhibiting antisocial behaviors are mainly due to the heterogeneity in etiologies, comorbidity inequality, and small sample size, especially in females.</p><p><strong>Objective: </strong>The study aimed to find sexual dimorphic brain regions associated with individual differences in antisocial behavior while avoiding the issues of heterogeneity and sample size.</p><p><strong>Methods: </strong>We collected structural neuroimaging data from 281 college students (131 males, 150 females) and analyzed the data using voxel-based morphometry.</p><p><strong>Results: </strong>The gray matter volume in three brain regions correlates with self-reported antisocial behavior in males and females differently: the posterior superior temporal sulcus, middle temporal gyrus, and precuneus. The findings have controlled for the total cortical gray matter volume, age, IQ, and socioeconomic status. Additionally, we found a common neural substrate of antisocial behavior in both males and females, extending from the anterior temporal lobe to the insula.</p><p><strong>Conclusion: </strong>This is the first neuroanatomical evidence from a large non-clinical sample of young adults. The study suggests that differences in males and females in reading social cues, understanding intentions and emotions, and responding to conflicts may contribute to the modulation of brain morphometry concerning antisocial behavior.</p>","PeriodicalId":93496,"journal":{"name":"Psychoradiology","volume":"3 ","pages":"kkad031"},"PeriodicalIF":0.0000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10917369/pdf/","citationCount":"0","resultStr":"{\"title\":\"Sex dimorphic cortical brain volumes associated with antisocial behavior in young adults.\",\"authors\":\"Ke Ding, Miao Xu, Taicheng Huang, Yiying Song, Feng Kong, Zonglei Zhen\",\"doi\":\"10.1093/psyrad/kkad031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Although sex differences in antisocial behavior are well-documented, the extent to which neuroanatomical differences are related to sex differences in antisocial behavior is unclear. The inconsistent results from different clinical populations exhibiting antisocial behaviors are mainly due to the heterogeneity in etiologies, comorbidity inequality, and small sample size, especially in females.</p><p><strong>Objective: </strong>The study aimed to find sexual dimorphic brain regions associated with individual differences in antisocial behavior while avoiding the issues of heterogeneity and sample size.</p><p><strong>Methods: </strong>We collected structural neuroimaging data from 281 college students (131 males, 150 females) and analyzed the data using voxel-based morphometry.</p><p><strong>Results: </strong>The gray matter volume in three brain regions correlates with self-reported antisocial behavior in males and females differently: the posterior superior temporal sulcus, middle temporal gyrus, and precuneus. The findings have controlled for the total cortical gray matter volume, age, IQ, and socioeconomic status. Additionally, we found a common neural substrate of antisocial behavior in both males and females, extending from the anterior temporal lobe to the insula.</p><p><strong>Conclusion: </strong>This is the first neuroanatomical evidence from a large non-clinical sample of young adults. The study suggests that differences in males and females in reading social cues, understanding intentions and emotions, and responding to conflicts may contribute to the modulation of brain morphometry concerning antisocial behavior.</p>\",\"PeriodicalId\":93496,\"journal\":{\"name\":\"Psychoradiology\",\"volume\":\"3 \",\"pages\":\"kkad031\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10917369/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychoradiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/psyrad/kkad031\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychoradiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/psyrad/kkad031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:尽管反社会行为的性别差异已得到充分证实,但神经解剖学差异与反社会行为性别差异的相关程度尚不清楚。不同临床人群表现出反社会行为的结果不一致,主要是由于病因的异质性、合并症的不平等性以及样本量较小,尤其是女性:本研究旨在寻找与反社会行为个体差异相关的性二态脑区,同时避免异质性和样本量问题:我们收集了 281 名大学生(131 名男生,150 名女生)的结构神经影像学数据,并使用基于体素的形态计量学方法对数据进行了分析:结果:男性和女性三个脑区的灰质体积与自我报告的反社会行为的相关性不同:后颞上沟、颞中回和楔前回。研究结果控制了大脑皮层灰质总量、年龄、智商和社会经济地位。此外,我们还发现男性和女性的反社会行为都有一个共同的神经基底,从颞叶前部一直延伸到脑岛:结论:这是首次从大量非临床样本的年轻成年人中获得的神经解剖学证据。研究表明,男性和女性在解读社会线索、理解意图和情绪以及应对冲突方面的差异,可能有助于调节有关反社会行为的大脑形态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Sex dimorphic cortical brain volumes associated with antisocial behavior in young adults.

Background: Although sex differences in antisocial behavior are well-documented, the extent to which neuroanatomical differences are related to sex differences in antisocial behavior is unclear. The inconsistent results from different clinical populations exhibiting antisocial behaviors are mainly due to the heterogeneity in etiologies, comorbidity inequality, and small sample size, especially in females.

Objective: The study aimed to find sexual dimorphic brain regions associated with individual differences in antisocial behavior while avoiding the issues of heterogeneity and sample size.

Methods: We collected structural neuroimaging data from 281 college students (131 males, 150 females) and analyzed the data using voxel-based morphometry.

Results: The gray matter volume in three brain regions correlates with self-reported antisocial behavior in males and females differently: the posterior superior temporal sulcus, middle temporal gyrus, and precuneus. The findings have controlled for the total cortical gray matter volume, age, IQ, and socioeconomic status. Additionally, we found a common neural substrate of antisocial behavior in both males and females, extending from the anterior temporal lobe to the insula.

Conclusion: This is the first neuroanatomical evidence from a large non-clinical sample of young adults. The study suggests that differences in males and females in reading social cues, understanding intentions and emotions, and responding to conflicts may contribute to the modulation of brain morphometry concerning antisocial behavior.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.50
自引率
0.00%
发文量
0
期刊最新文献
Functional connectivity analyses of individual hippocampal subregions in major depressive disorder with electroconvulsive therapy. A decade of white matter connectivity studies in developmental dyslexia. Development of the brain network control theory and its implications. Exploring methodological frontiers in laminar fMRI. Identifying brain targets for real-time fMRI neurofeedback in chronic pain: insights from functional neurosurgery.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1