运动员心肌肌钙蛋白升高的现有模式。

IF 1.1 Q4 RESPIRATORY SYSTEM Monaldi Archives for Chest Disease Pub Date : 2024-04-30 DOI:10.4081/monaldi.2024.2878
Mihail Celeski, Andrea Segreti, Mariagrazia Piscione, Luigi Maria Monticelli, Giuseppe Di Gioia, Chiara Fossati, Gian Paolo Ussia, Fabio Pigozzi, Francesco Grigioni
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引用次数: 0

摘要

众所周知,运动能改善心血管健康并延长寿命,但相当多的人也会因运动而导致心肌肌钙蛋白水平升高。多年来,研究人员一直在争论运动引起的心肌肌钙蛋白升高是生理反应还是病理反应的结果,以及它们是否具有临床意义。参加不同类型运动的运动员在心肌肌钙蛋白升高和心脏重塑方面存在差异。在预测运动引起的心肌肌钙蛋白升高时,还需要考虑许多其他参数,因为心肌肌钙蛋白升高的程度存在很大的个体间异质性。虽然以前认为运动员的心肌肌钙蛋白升高是一种良性现象,但最近的许多研究推翻了这一观点,证明在特定的个体中,心肌肌钙蛋白升高可能会对临床和预后产生影响。本综述旨在研究心肌肌钙蛋白在运动员中的作用及其在各种运动环境中的作用。本综述还讨论了潜在的预后和临床影响以及未来的研究方法,并提供了一个简单明了的逐步算法,帮助临床医生解释缺血和非缺血情况下运动员的心肌肌钙蛋白升高。
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The current paradigm of cardiac troponin increase among athletes.

Although it is known that exercise improves cardiovascular health and extends life expectancy, a significant number of people may also experience an elevation in cardiac troponin levels as a result of exercise. For many years, researchers have argued whether exercise-induced cardiac troponin rises are a consequence of a physiological or pathological reaction and whether they are clinically significant. Differences in cardiac troponin elevation and cardiac remodeling can be seen between athletes participating in different types of sports. When forecasting the exercise-induced cardiac troponin rise, there are many additional parameters to consider, as there is a large amount of interindividual heterogeneity in the degree of cardiac troponin elevation. Although it was previously believed that cardiac troponin increases in athletes represented a benign phenomenon, numerous recent studies disproved this notion by demonstrating that, in specific individuals, cardiac troponin increases may have clinical and prognostic repercussions. This review aims to examine the role of cardiac troponin in athletes and its role in various sporting contexts. This review also discusses potential prognostic and clinical implications, as well as future research methods, and provides a straightforward step-by-step algorithm to help clinicians interpret cardiac troponin rise in athletes in both ischemic and non-ischemic circumstances.

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CiteScore
3.60
自引率
0.00%
发文量
1
审稿时长
12 weeks
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