组织可塑性在精确发育中的新作用。

IF 3.8 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Biochemical Society transactions Pub Date : 2024-06-26 DOI:10.1042/BST20230173
Sundar Ram Naganathan
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引用次数: 0

摘要

可重复的组织形态是胚胎发育的一个基本特征。为了确保组织形态发生过程中的这种稳健性,必须缓冲生物过程中固有的噪音。众所周知,冗余基因、平行信号通路和错综复杂的网络拓扑结构可以减少噪音,而在过去几年中,组织的机械特性也被证明起着至关重要的作用。在这里,我将以躯干形状变化为例,讨论组织在改变形状方面的高度可塑性是如何提高精确性和可重复性的。
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An emerging role for tissue plasticity in developmental precision.

Reproducible tissue morphology is a fundamental feature of embryonic development. To ensure such robustness during tissue morphogenesis, inherent noise in biological processes must be buffered. While redundant genes, parallel signaling pathways and intricate network topologies are known to reduce noise, over the last few years, mechanical properties of tissues have been shown to play a vital role. Here, taking the example of somite shape changes, I will discuss how tissues are highly plastic in their ability to change shapes leading to increased precision and reproducibility.

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来源期刊
Biochemical Society transactions
Biochemical Society transactions 生物-生化与分子生物学
CiteScore
7.80
自引率
0.00%
发文量
351
审稿时长
3-6 weeks
期刊介绍: Biochemical Society Transactions is the reviews journal of the Biochemical Society. Publishing concise reviews written by experts in the field, providing a timely snapshot of the latest developments across all areas of the molecular and cellular biosciences. Elevating our authors’ ideas and expertise, each review includes a perspectives section where authors offer comment on the latest advances, a glimpse of future challenges and highlighting the importance of associated research areas in far broader contexts.
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