胆总管结石治疗的变化:1980年至今。

IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL Rambam Maimonides Medical Journal Pub Date : 2024-04-28 DOI:10.5041/RMMJ.10521
Ruth Stalnikowicz, Jochanan Benbassat
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引用次数: 0

摘要

目的比较通过内镜括约肌切开术(ES)、外科探查术或内镜括约肌切开术和外科CBD探查术(会合技术)联合治疗胆总管(CBD)结石患者的效果:方法:对文献进行叙述性回顾:1990 年以前,17 项队列研究表明,92.0% 的患者通过 ES 清除了 CBD 结石,死亡率为 1.5%。90.2%的患者通过手术清除了 CBD 结石,死亡率为 2.1%。1987 年的一项随机对照试验显示,在 55 名患者中,91% 的 CBD 结石患者通过 ES 清除了结石,死亡率为 3.6%,并发症发生率为 27%;而通过手术探查 CBD 结石的患者比例为 92%,死亡率为 1.8%,并发症发生率为 22%。自1991年以来,已有26项随机对照试验表明,腹腔镜-ES会合手术与单纯ES手术和单纯腹腔镜手术一样有效,但并发症更少,对额外手术的需求更低,住院时间更短:腹腔镜与腹腔镜联合手术似乎是治疗年轻、体格健壮的CBD结石患者的最佳方法。对于年龄较大或高危患者,在单纯ES和腹腔镜-ES交会术之间如何选择仍不确定。
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Changes in the Management of Common Bile Duct Stones: 1980 to Date.

Objective: To compare the results of treating patients with common bile duct (CBD) stones by endoscopic sphincterotomy (ES), surgical exploration, or a combination of ES and surgical CBD exploration (the rendezvous technique).

Methods: A narrative review of the literature.

Summary of data: Before 1990, 17 cohort studies indicated that ES cleared CBD stones in 92.0% of patients, with a mortality rate of 1.5%. Surgery removed CBD stones in 90.2% of patients, with a 2.1% mortality rate. A single randomized controlled trial in 1987 showed that ES removed CBD stones in 91% of 55 patients, with a 3.6% mortality rate and a 27% complication rate, whereas surgical CBD exploration removed CBD stones in 92%, with a 1.8% mortality rate and a 22% complication rate. Since 1991, 26 randomized controlled trials have shown that laparoscopic-ES rendezvous is as effective as ES alone and laparoscopic surgery alone but is associated with fewer complications, a reduced need for additional procedures, and a shorter hospital stay.

Conclusions: A laparoscopic-ES rendezvous appears to be the optimal approach to the treatment of CBD stones in younger and fit patients. The choice between ES alone and laparoscopic-ES rendezvous in older or high-risk patients remains uncertain.

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来源期刊
Rambam Maimonides Medical Journal
Rambam Maimonides Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
6.70%
发文量
55
审稿时长
8 weeks
期刊最新文献
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