圣保罗一家医院急性手部感染的流行病学特征是什么?

IF 0.5 4区 医学 Q4 ORTHOPEDICS Acta Ortopedica Brasileira Pub Date : 2024-05-06 eCollection Date: 2024-01-01 DOI:10.1590/1413-785220243201e277229
Thomas Yi Teh Lee, Lucas Alves Nemer, Alessandro Ayres Vianna, Yussef Ali Abdouni, Fabrício Luz Cardoso, Antonio Carlos da Costa
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引用次数: 0

摘要

目的确定在一家位于重要城市中心的骨科和创伤科专科慈善医院接受治疗的患者的流行病学概况,并评估初始经验性抗生素治疗的疗效:方法:纳入 2020 年 9 月至 2022 年 9 月期间诊断为手部感染的患者,排除与开放性骨折或手术后感染有关的病例以及病历不完整的病例。使用 STATISTICA ® 软件进行卡方检验,对各种变量进行相关性分析:共有 34 名患者参与研究,包括 24 名男性和 10 名女性,平均年龄为 41.9 岁。大多数男性患者患有糖尿病、艾滋病和毒瘾,居住在城市地区。半数患者未报告任何明显外伤。最常见的感染病原体是金黄色葡萄球菌*。近 62% 的患者需要改变最初的抗生素治疗方案,其中青霉素是最常用的替代药物。β-内酰胺类抗生素和喹诺酮类药物最为有效:这些结果表明,仔细评估急性手部感染患者的流行病学特征并改进初始经验性治疗以确保治疗适当有效非常重要。证据等级 IV,横断面观察研究。
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WHAT IS THE EPIDEMIOLOGICAL PROFILE OF ACUTE HAND INFECTIONS AT A HOSPITAL IN SAO PAULO?

Objective: To determine the epidemiological profile of patients treated at a philanthropic hospital specialized in Orthopedics and Traumatology, located in a significant urban center, and evaluate the efficacy of initial empirical antibiotic treatment.

Methods: Patients diagnosed with hand infections from September 2020 to September 2022 were included, excluding cases related to open fractures or post-surgical infections and those with incomplete medical records. The chi-square test was performed using STATISTICA ® software to correlate various variables.

Results: A total of 34 patients participated, including 24 men and 10 women, with an average age of 41.9 years. Most male patients had Diabetes Mellitus, HIV, and drug addiction, and they resided in urban areas. Half of the patients did not report any apparent trauma. The most common infectious agent was Staphylococcus aureus*. Nearly 62% of patients required a change in the initial antibiotic regimen, with Penicillin being the most frequently substituted medication. Beta-lactam antibiotics and Quinolones were the most effective.

Conclusion: These results suggest the importance of carefully evaluating the epidemiological profile of patients with acute hand infections and improving initial empirical treatment to ensure appropriate and effective therapy. Level of Evidence IV, Cross-Sectional Observational Study.

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来源期刊
CiteScore
0.90
自引率
14.30%
发文量
67
审稿时长
25 weeks
期刊介绍: A Revista Acta Ortopédica Brasileira, órgão oficial do Departamento de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo (DOT/FMUSP), é publicada bimestralmente em seis edições ao ano (jan/fev, mar/abr, maio/jun, jul/ago, set/out e nov/dez) com versão em inglês disponível nos principais indexadores nacionais e internacionais e instituições de ensino do Brasil. Sendo hoje reconhecidamente uma importante contribuição para os especialistas da área com sua seriedade e árduo trabalho para as indexações já conquistadas.
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