用静脉体外膜氧合治疗嗜铬细胞瘤引起的复发性塔克次氏心肌病

Journal of medical cases Pub Date : 2024-05-01 Epub Date: 2024-05-02 DOI:10.14740/jmc4195
Georgia Karmioti, Stefanos Sakellaropoulos, Inan Sarikaya, Antonia Kastoris, Christina Hadjilouka, Christos Efseviou, Michael Myrianthefs, Andreas Mitsis
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引用次数: 0

摘要

嗜铬细胞瘤诱发的塔克次氏心肌病是一种罕见但危及生命的疾病,由血浆儿茶酚胺水平过高引起,导致急性心肌功能障碍。临床表现包括由于区域性室壁运动异常(最常见的是影响所有左心室(LV)壁中段至心尖段)导致左心室呈 "章鱼陷阱状 "而迅速发展为心力衰竭。一名 45 岁的女性患者因非缺血性急性心源性休克就诊。她的既往病史中曾有一次类似的病例,之后完全康复,但这次入院时需要静脉体外膜氧合的血液动力学支持。收缩功能恢复后,进一步检查发现 24 小时尿中的肾上腺素水平较高,左肾上腺有肿块,诊断为嗜铬细胞瘤。先用α-受体阻滞剂,后用β-受体阻滞剂治疗后,手术切除了嗜铬细胞瘤。
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Recurrent Takotsubo Cardiomyopathy due to Pheochromocytoma Managed With Venoarterial Extracorporeal Membrane Oxygenation.

Pheochromocytoma-induced Takotsubo cardiomyopathy is a rare but life-threatening condition, caused by excessive plasma catecholamine levels, resulting in acute myocardial dysfunction. Clinical presentation includes a rapid development of heart failure due to regional wall motion abnormalities (most commonly affecting all mid to apical left ventricle (LV) wall segments) causing the "octopus-trap-like" LV shape. A 45-year-old female patient presented with acute cardiogenic shock of non-ischemic etiology. Her past medical history included a similar episode, which was followed by full recovery, but at this admission she required hemodynamic support with venoarterial extracorporeal membrane oxygenation. The systolic function was restored, and further investigation revealed high 24-h urine metanephrine levels and a mass of the left adrenal gland, leading to the diagnosis of pheochromocytoma. After treatment with firstly alpha-blockers and then beta-blockers, the pheochromocytoma was surgically removed.

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