黄酮类化合物是预防和治疗湿疹的潜在天然化合物。

Javed Khan, Shikha Yadav, Divya Bhardwaj, Abhishek Kumar, Moshood Ummuani Okanlawon
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引用次数: 0

摘要

湿疹是一种全身性自身免疫性疾病,以炎症和皮肤表现为特征,并伴有一系列合并症,包括生理和心理障碍。尽管近年来在了解特应性皮炎的发病机制方面取得了进展,但目前市场上销售的产品效果不一,副作用较多。目前研究的目标是开发治疗湿疹的新药物,以降低现有新型药物的成本,同时提高疗效,减少不良反应。自古以来,人们一直使用天然化合物和药用植物。如今,草药领域的研究正处于高峰期。其中一种天然化合物黄酮类化合物被发现对治疗湿疹有益。本综述介绍了如何使用某些类黄酮产品来配制适合治疗湿疹的制剂。尤其是在预防或治疗特应性湿疹方面。这些化合物表现出抗炎、消炎、抗发炎的特性,因此可用于预防过敏、炎症和刺激皮肤的治疗。我们还将所用的类黄酮衍生物与抑制湿疹的相关蛋白质对接,以更好地优化引线。这些制剂似乎可用于化妆品、皮肤病或草药的局部治疗。
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Flavonoids as Potential Natural Compounds for the Prevention and Treatment of Eczema.

Eczema is a systemic autoimmune disease characterized by inflammation and skin manifestation with a range of comorbidities that include physical and psychological disorders. Despite recent advancements in understanding the mechanisms involved in atopic dermatitis, current marketed products have shown varying results with more side effects. The present objective of the research studies is to develop new agents for eczema that cut down the cost of the novel drugs available and also improve the efficacy with the least adverse effects. Natural compounds and medicinal plants have been traditionally used since ancient civilizations. Nowadays, research in the herbal field is at its peak. One such natural compound, flavonoid, was found to be beneficial for the treatment of eczema. This review describes the use of certain flavonoid products to prepare preparations suitable for the treatment of prophylaxis or eczema. This is especially true for prophylaxis or atopic eczema treatment. These compounds exhibit anti-inflammatory, anti-inflammatory, anti-inflammatory, and anti-inflammatory properties and are, therefore, used in treatments to prevent allergies, inflammation, and irritation to the skin. We also dock the flavonoid derivatives used with the protein associated with the inhibition of eczema for better lead optimization. These preparations appear to be used for cosmetic, dermatological, or herbal remedies as a local application.

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