寻求治疗的 AUD 患者的奖励、解脱和习惯性饮酒概况。

IF 2.1 4区 医学 Q3 SUBSTANCE ABUSE Alcohol and alcoholism Pub Date : 2024-03-16 DOI:10.1093/alcalc/agae032
Erica N Grodin, Wave-Ananda Baskerville, Lindsay R Meredith, Steven Nieto, Lara A Ray
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引用次数: 0

摘要

目的:本研究旨在比较寻求奖励、解脱和习惯治疗的个体在近期饮酒、酒精使用障碍(AUD)现象和情绪方面的情况。研究的第二个目的是评估奖励、缓解和习惯档案的预测有效性:方法:招募寻求治疗的 AUD 患者(n = 169)参加 AUD 药物试验(NCT03594435)。采用加州大学洛杉矶分校奖励缓解习惯性饮酒量表对奖励、缓解和习惯性饮酒组进行评估。采用单变量方差分析评估基线时的组间差异。一部分参与者参加了为期 12 周的双盲安慰剂对照药物试验(n = 102),并提供了纵向饮酒和现象学数据。通过线性回归分析评估了群体成员资格的预测有效性:结果:基线时,与为奖励和习惯而饮酒的人相比,主要为解乏而饮酒的人有更高的渴求度和消极情绪。展望未来,与奖励性饮酒组相比,解脱性饮酒组的成员预示着更大的酒精使用量、更大的重度饮酒量和更少的戒酒天数。与奖励性饮酒组相比,解脱性饮酒组的成员在12周内对酒精的渴望程度更高,与酒精相关的后果更多,焦虑症状更多:本研究为寻求治疗的 AUD 患者的奖赏型和解脱型饮酒动机特征提供了支持。解脱型饮酒动机组的成员可预测较差的饮酒结果和12周内更多的消极症状,这表明为解脱而饮酒的人可能是AUD患者中一个特别脆弱的亚群体。
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Reward, relief, and habit drinking profiles in treatment seeking individuals with an AUD.

Aims: This study aimed to compare reward, relief, and habit treatment-seeking individuals on recent drinking, alcohol use disorder (AUD) phenomenology, and mood. The second aim of the study was to evaluate the predictive validity of reward, relief, and habit profiles.

Method: Treatment-seeking individuals with an AUD (n = 169) were recruited to participate in a medication trial for AUD (NCT03594435). Reward, relief, and habit drinking groups were assessed using the UCLA Reward Relief Habit Drinking Scale. Group differences at baseline were evaluated using univariate analyses of variance. A subset of participants were enrolled in a 12-week, double-blind, placebo-controlled medication trial (n = 102), and provided longitudinal drinking and phenomenology data. The predictive validity of group membership was assessed using linear regression analyses.

Results: At baseline, individuals who drink primarily for relief had higher craving and negative mood than those who drink for reward and habit. Prospectively, membership in the relief drinking group predicted greater alcohol use, greater heavy drinking, and fewer days abstinent compared to those in the reward drinking group. Membership in the relief drinking group also predicted greater alcohol craving, more alcohol-related consequences, and more anxiety symptoms over 12 weeks compared to those in the reward drinking group.

Conclusions: This study provides support for reward and relief drinking motive profiles in treatment-seeking individuals with an AUD. Membership in the relief drinking motive group was predictive of poorer drinking outcomes and more negative symptomology over 12 weeks, indicating that individuals who drink for relief may be a particularly vulnerable sub-population of individuals with AUD.

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来源期刊
Alcohol and alcoholism
Alcohol and alcoholism 医学-药物滥用
CiteScore
4.70
自引率
3.60%
发文量
62
审稿时长
4-8 weeks
期刊介绍: About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.
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