[18F]FDG正电子发射计算机断层扫描(PET/CT)用于确定不明原因发热(FUO)的病因。

IF 2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING American journal of nuclear medicine and molecular imaging Pub Date : 2024-04-25 eCollection Date: 2024-01-01 DOI:10.62347/OQQC6007
Shashi B Singh, Niki Shrestha, Sadikshya Bhandari, Suprita Shrestha, Bijay Shrestha, Neharika Shrestha, Swarnima Rijal, Rajshree Singh, Soren Hess, Thomas J Werner, Abass Alavi, Mona-Elisabeth Revheim
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引用次数: 0

摘要

不明原因发热(FUO)仍然是临床医学中极具挑战性的诊断方法。它有 200 多种已知病因,包括感染、自身免疫性疾病、肿瘤和其他杂症。尽管已开发出多种诊断工具,但目前还没有针对 FUO 的特定诊断算法。不过,[18F]FDG PET/CT 除了能提供器官解剖细节外,还能提供细胞代谢信息,已被证明能成功用于 FUO 检查。本研究强调了[18F]FDG PET/CT 在诊断各种原因的 FUO 中的应用。[18F]FDG正电子发射计算机断层显像/CT越来越多地用于检测化脓性感染、无菌性炎症过程和恶性肿瘤,在已知的FUO病因中占了很大一部分。它使 FUO 的病因鉴定更加明确,临床治疗更加准确。然而,要了解[18F]FDG PET/CT 是否可用于 FUO 的检查,更深入的研究至关重要。
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[18F]FDG PET/CT for identifying the causes of fever of unknown origin (FUO).

Fever of unknown origin (FUO) continues to be a challenging diagnosis in clinical medicine. It has more than 200 known causes, including infections, autoimmune diseases, neoplasia, and other miscellaneous disorders. Despite the development of a wide range of diagnostic tools, a specific diagnostic algorithm for FUO is not yet available. However, [18F]FDG PET/CT, which yields information on cellular metabolism, in addition to details of organ anatomy, has been shown to be successful in the FUO investigation. This study highlights the uses of [18F]FDG PET/CT in diagnosing various causes of FUO. [18F]FDG PET/CT has been increasingly used to detect septic infections, sterile inflammatory processes, and malignancies, occupying a significant portion of the known causes of FUO. It has led to a more definitive identification of the etiology of FUO and accurate clinical management. However, more in-depth studies are crucial to understanding if [18F]FDG PET/CT can be used in the work-up of FUO.

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来源期刊
American journal of nuclear medicine and molecular imaging
American journal of nuclear medicine and molecular imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
4.00%
发文量
4
期刊介绍: The scope of AJNMMI encompasses all areas of molecular imaging, including but not limited to: positron emission tomography (PET), single-photon emission computed tomography (SPECT), molecular magnetic resonance imaging, magnetic resonance spectroscopy, optical bioluminescence, optical fluorescence, targeted ultrasound, photoacoustic imaging, etc. AJNMMI welcomes original and review articles on both clinical investigation and preclinical research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.
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