[与斯约格伦综合征相关的周围神经和肌肉疾病]。

Q3 Medicine Brain and Nerve Pub Date : 2024-05-01 DOI:10.11477/mf.1416202648
Hiroya Kuwahara, Takanori Yokota
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引用次数: 0

摘要

斯约格伦综合征通常伴有各种神经系统并发症,其中最常见的是周围神经病变。文献报道了多种周围神经病变的临床表型,包括轴索多发性神经病变和感觉共济失调性神经病变。我们将概述每种表型的病理生理学和鉴别诊断。使用皮质类固醇和大剂量静脉注射免疫球蛋白的免疫疗法往往会根据周围神经病变表型的不同而产生不同的治疗反应。我们还讨论了斯约格伦综合征可能并发的肌炎。
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[Peripheral Nerve and Muscle Disorders Associated with Sjögren's Syndrome].

Sjögren's syndrome is often accompanied by various neurological complications, among which peripheral neuropathy is the most common. A variety of clinical phenotypes of peripheral neuropathy, including axonal polyneuropathy and sensory ataxic neuropathy are reported in the literature. We present an overview of the pathophysiology and differential diagnosis of each phenotype. Immunotherapy using corticosteroids and high-dose intravenous immunoglobulin therapy tends to elicit varied therapeutic responses depending on the peripheral neuropathy phenotype. We also discuss myositis, a possible complication of Sjögren's syndrome.

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Brain and Nerve
Brain and Nerve Medicine-Neurology (clinical)
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