免疫力低下儿童的后可逆性脑病综合征--来自南印度的一项单中心研究。

IF 0.8 Q4 CLINICAL NEUROLOGY Journal of Neurosciences in Rural Practice Pub Date : 2024-04-01 Epub Date: 2024-02-13 DOI:10.25259/JNRP_390_2023
Sudeep Gaddam, Rajesh Kodandapani, Nikhita Mani, Dhaarani Jayaraman, B Nikitha Abirami
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引用次数: 0

摘要

本研究描述了在儿科血液肿瘤科确诊的后可逆性脑病综合征(PRES)患儿的概况,并强调了免疫抑制儿童 PRES 的临床特征。这项回顾性研究纳入了10名被诊断患有PRES的儿童,他们的平均年龄为6.8岁。急性淋巴细胞白血病是最常见的主要诊断,其次是造血干细胞移植后患者。大多数PRES病例发生在开始治疗的一个月内。所有患者在确诊时都患有高血压。神经影像学检查发现双侧病变,顶叶和枕叶受累最为常见。所有患者在初诊时都接受了皮质类固醇治疗。控制血压是治疗 PRES 的关键。在儿科血液肿瘤科,如果儿童出现头痛、癫痫发作和视力障碍等症状,考虑到PRES的临床可能性,将有助于在排除引起这些症状的其他原因后进行早期诊断。
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Posterior reversible encephalopathy syndrome in immunocompromised children - A single-center study from South India.

This study describes the profile of children diagnosed with posterior reversible encephalopathy syndrome (PRES) in the pediatric hematology oncology unit and highlights the clinical features of PRES in immunosuppressed children. This retrospective study included 10 children diagnosed with PRES with a mean age of 6.8 years. Acute lymphoblastic leukemia was the most common primary diagnosis followed by post-hematopoietic stem cell transplant patients. Most cases of PRES occurred within one month of treatment initiation. Hypertension was noted in all at the time of diagnosis. Neuroimaging revealed bilateral lesions with parietal and occipital lobe involvement being the most common. All patients received corticosteroids as part of treatment for primary diagnosis. Controlling blood pressure was critical in managing PRES. Consideration of PRES as a clinical possibility in pediatric hematology oncology unit in children presenting with symptoms such as headache, seizures, and visual disturbances will aid in early diagnosis after ruling out other causes of these symptoms.

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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
129
审稿时长
22 weeks
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