在新药上市的背景下西班牙治疗 ITP 的实际临床实践。基于德尔菲法的西班牙专家小组共识。

IF 2.5 3区 医学 Q3 CELL BIOLOGY Platelets Pub Date : 2024-12-01 Epub Date: 2024-05-14 DOI:10.1080/09537104.2024.2336104
Tomás José González-López, Abelardo Bárez, Ángel Bernardo-Gutiérrez, Silvia Bernat, Fernando Fernández-Fuertes, José María Guinea de Castro, Reyes Jiménez-Bárcenas, Isidro Jarque
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引用次数: 0

摘要

免疫性血小板减少症(ITP)是一种常见的自身免疫性血液病。尽管如此,由于临床异质性和缺乏特异性诊断测试,诊断仍具有挑战性。病理方面的新发现和新药的出现促使全球制定了不同的指南。在本研究中,我们采用了德尔菲方法,以就西班牙成年 ITP 患者的管理达成共识,并帮助做出决策。德尔菲问卷由一个科学特设委员会设计,分为 13 个主题,共有 127 个项目,涵盖了治疗 ITP 的最大可能情况。研究结果显示,达成共识的比例高达 81%。结论是,德尔菲共识就有关 ITP 患者诊断和管理的主题提供了实用建议,以帮助医生改善治疗效果。有些方面仍不明确,专家们也未达成共识。因此,需要取得更多进展,以优化 ITP 管理。
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Real-life clinical practice in Spain in the setting of new drug availability for ITP treatment. A Delphi-based Spanish expert panel consensus.

Immune thrombocytopenia (ITP) is a common autoimmune hematological disorder. Despite this, diagnosis is still challenging due to clinical heterogeneity and the lack of a specific diagnostic test. New findings in the pathology and the availability of new drugs have led to the development of different guidelines worldwide. In the present study, the Delphi methodology has been used to get a consensus on the management of adult patients with ITP in Spain and to help in decision-making. The Delphi questionnaire has been designed by a scientific ad hoc committee and has been divided into 13 topics, with a total of 127 items, covering the maximum possible scenarios for the management of ITP. As a result of the study, a total consensus of 81% has been reached. It is concluded that this Delphi consensus provides practical recommendations on topics related to diagnosis and management of ITP patients to help doctors to improve outcomes. Some aspects remain unclear, without consensus among the experts. Thus, more advances are needed to optimize ITP management.

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来源期刊
Platelets
Platelets 医学-细胞生物学
CiteScore
6.70
自引率
3.00%
发文量
79
审稿时长
1 months
期刊介绍: Platelets is an international, peer-reviewed journal covering all aspects of platelet- and megakaryocyte-related research. Platelets provides the opportunity for contributors and readers across scientific disciplines to engage with new information about blood platelets. The journal’s Methods section aims to improve standardization between laboratories and to help researchers replicate difficult methods. Research areas include: Platelet function Biochemistry Signal transduction Pharmacology and therapeutics Interaction with other cells in the blood vessel wall The contribution of platelets and platelet-derived products to health and disease The journal publishes original articles, fast-track articles, review articles, systematic reviews, methods papers, short communications, case reports, opinion articles, commentaries, gene of the issue, and letters to the editor. Platelets operates a single-blind peer review policy. Authors can choose to publish gold open access in this journal.
期刊最新文献
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