合成电纺纤维伤口基质在处理复杂创伤伤口中的协同临床应用:左腹股沟和大腿螺旋损伤的脱脂治疗。

IF 1.4 4区 医学 Q3 DERMATOLOGY Wounds : a compendium of clinical research and practice Pub Date : 2024-04-01
Luis G Fernandez, Carolina Orsi, Brandon Okeoke, Paige Moudy, Paul A Critelli, Scott Norwood, Marc R Matthews, Paul J Kim, Matthew MacEwan, Emily Sallade
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引用次数: 0

摘要

背景:处理涉及大面积的复杂创伤性软组织伤口,同时努力优化愈合、避免感染并促进良好的美容效果,是一项具有挑战性的工作。ECM 等再生材料通常用于伤口护理,以增强伤口愈合反应和组织形成的增殖阶段:本文报告的病例是在手术治疗涉及左下肢和下腹部的大型复杂创伤伤口时有效使用 SEFM 的实例。在 1200 平方厘米的面积上,成功地为植皮准备好了伤口床,这也是文献中报道的 SEFM 最大应用范围之一:本病例报告展示了SEFM的临床多功能性以及复杂创伤伤口护理的协同方法。在地形复杂的解剖区域,SEFM 成功地实现了大面积的组织肉芽化,并成功地进行了皮肤移植。
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Synergistic clinical application of synthetic electrospun fiber wound matrix in the management of a complex traumatic wound: degloving left groin and thigh auger injury.

Background: Managing complex traumatic soft tissue wounds involving a large surface area while attempting to optimize healing, avoid infection, and promote favorable cosmetic outcomes is challenging. Regenerative materials such as ECMs are typically used in wound care to enhance the wound healing response and proliferative phase of tissue formation.

Case report: The case reported herein is an example of the efficacious use of an SEFM in the surgical management of a large complex traumatic wound involving the left lower extremity and lower abdominal region. The wound bed was successfully prepared for skin grafting over an area of 1200 cm2, making this among the largest applications of the SEFM reported in the literature.

Conclusion: This case report demonstrates the clinical versatility of the SEFM and a synergistic approach to complex traumatic wound care. The SEFM was successfully used to achieve tissue granulation for a successful skin graft across a large surface in an anatomic region with complex topography.

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来源期刊
CiteScore
1.50
自引率
11.80%
发文量
77
审稿时长
6-12 weeks
期刊介绍: Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.
期刊最新文献
Diving deep into healing: the promising role of fish skin in wound recovery. Effectiveness of negative pressure wound therapy in treating diabetic foot ulcers: a systematic review and meta-analysis of randomized controlled trials. Evaluating the number of cellular and/or tissue-based product applications required to treat diabetic foot ulcers and venous leg ulcers in non-hospital outpatient department settings. Skin cancer or locally advanced mammary carcinoma: a discussion of cutaneous pathology on the male chest. Use of silver collagen oxidized regenerated cellulose dressings in conjunction with negative pressure wound therapy: expert panel consensus recommendations.
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