虚拟胰岛素泵对患有 1 型糖尿病的儿童青少年安全有效。

Frontiers in clinical diabetes and healthcare Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI:10.3389/fcdhc.2024.1362627
Benjamin Udoka Nwosu, Margaret Pellizzari, Maia N Pavlovic, Jason Ciron, Rashida Talib, Rubab Sohail
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引用次数: 0

摘要

目的:在美国,还没有对 1 型糖尿病青少年患者使用虚拟胰岛素泵和在诊室使用胰岛素泵的安全性和有效性进行正面比较。本研究旨在确定虚拟泵与诊室胰岛素泵在儿童 1 型糖尿病患者中的安全性和有效性:研究设计和方法:对 112 名受试者进行纵向回顾性研究:65%的受试者(n=73)接受了诊室培训,年龄为(11.2 ± 3.8)岁;35%的受试者(n=39)接受了虚拟培训,年龄为(12.0 ± 4.0)岁。白人受试者有 40 人(55%)在诊所组,25 人(66%)在远程组;黑人受试者有 11 人(15%)在诊所组,4 人(10%)在虚拟组。数据收集时间为泵启动、3 个月和 6 个月:结果:各组在性别、种族、身高、体重、体重指数和糖尿病病程方面均无明显差异。在 0 个月、3 个月和 6 个月时,各组的 A1c 无明显差异。在 0、3 和 6 个月时,A1c 与血糖管理指标有明显的相关性:基线:r=0.49,p 结论:虚拟胰岛素泵的启动是有效的:虚拟胰岛素泵对 1 型糖尿病儿童患者安全有效。这种方法可加快美国少数群体使用糖尿病技术的步伐。
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Virtual insulin pump initiation is safe effective in children adolescents with type 1 diabetes.

Objective: There is no head-to-head comparison of the safety and efficacy of virtual versus in-office insulin pump initiation for youth with type 1 diabetes in the US. The study's aim was to determine the safety and efficacy of virtual versus in-office pump initiation in pediatric type 1 diabetes.

Research design and methods: A longitudinal retrospective study of 112 subjects: 65% (n=73), ages 11.2 ± 3.8 years(y), received in-office training; and 35% (n=39), ages 12.0 ± 4.0y, received virtual training. The number of White subjects was 40 (55%) in the in-office group, and 25 (66%) in the remote group; while Black subjects were 11 (15%) in the in-office group and 4 (10%) in the virtual group. Data were collected at pump initiation, 3 and 6 months.

Results: There were no significant differences in sex, race, height, weight, BMI, and the duration of diabetes between the groups at baseline. There was no significant difference in A1c between the groups at 0, 3, and 6 months. A1c correlated significantly with the glucose management indicator at 0, 3, and 6 months: baseline: r=0.49, p<0.0001; 3 months: r=0.77, p<0.0001; and 6 months: r=0.71, p<0.0001. There was no relationship between A1c or TIR and pubertal status, BMI, sex, or race. A1c was significantly elevated in the non-White individuals at 6 months only: 57.9 mmol/mol (50.8-69.4) versus 51.9 mmol/mol (46.5-59.6)], p=0.007.

Conclusion: Virtual insulin pump initiation is safe and effective in children with type 1 diabetes. This approach could accelerate the adoption of the use of diabetes technology in minority populations in the US.

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