Khaled A. Aldwoah, Mohammed A. Almalahi, Manel Hleili, Faez A. Alqarni, Elkhateeb S. Aly, Kamal Shah
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Analytical study of a modified-ABC fractional order breast cancer model
This study investigates breast cancer dynamics using modified ABC-fractional operators. We examine interactions among cancer stem cells, tumor cells, healthy cells, excess estrogen effects, and immune cells. By applying the “Localization of Compact Invariant Sets” technique and comparison theory, we establish conditions for cancer persistence without immune cells and eradication with an immune response. We analyze equilibria, global attraction persistence state, stability, solution uniqueness, and existence using recursive sequences and fixed point theorem. Numerical simulations with Lagrange’s interpolation validate and deepen our understanding of breast cancer dynamics. Incorporating modified ABC-fractional derivatives enhances our comprehension of the model.
期刊介绍:
JAMC is a broad based journal covering all branches of computational or applied mathematics with special encouragement to researchers in theoretical computer science and mathematical computing. Major areas, such as numerical analysis, discrete optimization, linear and nonlinear programming, theory of computation, control theory, theory of algorithms, computational logic, applied combinatorics, coding theory, cryptograhics, fuzzy theory with applications, differential equations with applications are all included. A large variety of scientific problems also necessarily involve Algebra, Analysis, Geometry, Probability and Statistics and so on. The journal welcomes research papers in all branches of mathematics which have some bearing on the application to scientific problems, including papers in the areas of Actuarial Science, Mathematical Biology, Mathematical Economics and Finance.