未老先衰?骨关节炎对年轻人的影响

IF 3.7 2区 医学 Q1 RHEUMATOLOGY Arthritis Care & Research Pub Date : 2024-05-15 DOI:10.1002/acr.25374
Jessica M. Wilfong, Elizabeth M. Badley, Anthony V. Perruccio
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引用次数: 0

摘要

目的:骨关节炎(OA)通常被认为是一种老年疾病,是衰老的必然结果。由于对 OA 的研究通常仅限于老年人,因此有关年轻人 OA 的信息非常有限。本研究描述了不同年龄段人群的 OA 负担,并对年轻人和老年人进行了比较:方法:对《加拿大慢性病患者生活调查-关节炎部分》进行描述性分析,该调查具有全国代表性,调查对象为在加拿大社区健康调查(一项普通健康人口调查)中报告确诊为关节炎的 20 岁以上加拿大人。分析仅限于报告有 OA 且无其他类型关节炎的人(n=1,749):在具有代表性的 OA 患者群体中,55.4% 的人年龄小于 65 岁。确诊时的平均年龄为50岁,其中30.4%在45岁之前确诊。在受影响关节部位的平均数量、疼痛和疲劳的严重程度以及活动限制方面,年轻成人与患有 OA 的老年患者的症状严重程度相似。在最年轻的年龄组中,与普通人群相比,患有OA的人更有可能报告总体健康状况一般/较差、精神健康状况较差以及对生活不满意;而在最年长的年龄组中,情况并非如此:结论:OA 在中青年人中并不少见,他们受到的 OA 影响与老年人不相上下。这表明,患有 OA 的年轻人将带着症状和残疾生活很多年,并强调了跨年龄段有效管理 OA 的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Old Before Their Time? The Impact of Osteoarthritis on Younger Adults

Objective

Osteoarthritis (OA) is frequently perceived as a disease of the elderly and an inevitable result of aging. Because OA studies often are restricted to older adults, there is limited information on OA in younger adults. This study describes the burden of OA across a wide age range and compares younger and older adults.

Methods

Descriptive analysis of the Survey on Living with Chronic Diseases in Canada – Arthritis Component, a nationally representative survey of Canadians ≥20 years who reported an arthritis diagnosis in the Canadian Community Health Survey, a general health population survey. Analyses were restricted to those reporting OA and no other kind of arthritis (n = 1,749).

Results

In the representative group with OA, 55.4% were younger than 65 years. The mean age at diagnosis was 50 years, with 30.4% reporting being diagnosed before age 45 years. Younger adults reported similar symptom severity as their older counterparts with OA regarding the mean number of affected joint sites, severity of pain and fatigue, and activity limitations. In the youngest age group, those with OA were significantly more likely to report fair or poor overall and mental health and life dissatisfaction compared with their general counterparts; the same was not the case in the oldest age group.

Conclusion

OA is not uncommon among younger and middle-aged adults, and they experience OA impacts comparable with those for older adults. These findings suggest that younger adults with OA will live many years with symptoms and disability and highlight a need for effective OA management across ages.

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来源期刊
CiteScore
9.40
自引率
6.40%
发文量
368
审稿时长
3-6 weeks
期刊介绍: Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Health Professionals (a division of the College), is a peer-reviewed publication that publishes original research, review articles, and editorials that promote excellence in the clinical practice of rheumatology. Relevant to the care of individuals with rheumatic diseases, major topics are evidence-based practice studies, clinical problems, practice guidelines, educational, social, and public health issues, health economics, health care policy, and future trends in rheumatology practice.
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