在矫形外科创伤后全厚伤口缺损中使用 MatriDerm 和裂厚皮肤移植:病例报告和文献系统回顾。

IF 0.5 4区 医学 Q4 ORTHOPEDICS Journal of the American Podiatric Medical Association Pub Date : 2024-03-01 DOI:10.7547/22-009
Ioannis S Vasios, Konstantinos G Makiev, Paraskevas Georgoulas, Athanasios Ververidis, Georgios Drosos, Konstantinos Tilkeridis
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引用次数: 0

摘要

对于矫形外科医生来说,处理复杂和严重的下肢损伤具有挑战性。当无法进行主要或次要的缺损闭合时,就需要进行复杂的移植(分厚或全厚)或皮瓣(有蒂或游离)手术。这些手术由专门的整形外科医生进行,不良反应风险很高,甚至会导致供体和受体部位的高发病率。此外,分层厚皮移植(STSG)由于缺乏下层真皮组织,在机械稳定性、柔韧性和美观性方面的效果往往不能令人满意。因此,MatriDerm(MedSkin Solutions Dr Suwelack AG,德国比勒贝克)等真皮替代品已被提出并进一步开发,作为一种治疗方案,与 STSGs 一起用于处理全厚伤口缺损。我们旨在介绍一例因外伤截肢后使用 MatriDerm 结合自体 STSG 治疗左足全厚伤口缺损的病例。此外,我们还对文献进行了系统性回顾,以明确在骨科病例中使用 MatriDerm 结合 STSG 的疗效。
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Use of MatriDerm with Split-Thickness Skin Graft in Post-traumatic Full-Thickness Wound Defects in Orthopedic Cases: A Case Report and Systematic Review of the Literature.

The management of complex and severe lower-extremity injuries is challenging for the orthopedic surgeon. When the primary or secondary closure of the defect is not feasible, complex procedures with graft (split-thickness or full-thickness) or flap (pedicled or free) are required. These procedures are performed by specialized plastic surgeons and are at high risk for adverse effects, even high morbidity among both the donor and acceptor sites. Furthermore, split-thickness skin grafts (STSGs) often lead to unsatisfactory results in terms of mechanical stability, flexibility, and aesthetics due to the lack of underlying dermal tissue. Consequently, dermal substitutes, such as MatriDerm (MedSkin Solutions Dr Suwelack AG, Billerbeck, Germany), have been proposed and further developed as a treatment option addressing the management of full-thickness wound defects in conjunction with STSGs. We aimed to present a case of post-traumatic full-thickness wound defect of the left foot after traumatic amputation of the digits that was treated with MatriDerm combined with autologous STSG. In addition, we performed a systematic review of the literature to delineate the efficacy of the use of MatriDerm combined with STSGs in orthopedic cases exclusively.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
128
审稿时长
6-12 weeks
期刊介绍: The Journal of the American Podiatric Medical Association, the official journal of the Association, is the oldest and most frequently cited peer-reviewed journal in the profession of foot and ankle medicine. Founded in 1907 and appearing 6 times per year, it publishes research studies, case reports, literature reviews, special communications, clinical correspondence, letters to the editor, book reviews, and various other types of submissions. The Journal is included in major indexing and abstracting services for biomedical literature.
期刊最新文献
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