肝细胞癌治疗的进展:18F-FDG PET-CT 在诊断门静脉肿瘤血栓中的作用。

IF 1.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Nuclear Medicine Communications Pub Date : 2024-08-01 Epub Date: 2024-05-17 DOI:10.1097/MNM.0000000000001863
Raluca Mititelu, Alexandru Mitoi, Catalin Mazilu, Mariana Jinga, Florentina Ionita Radu, Ana Bucurica, Teodora Mititelu, Sandica Bucurica
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引用次数: 0

摘要

门静脉血栓是与肝细胞癌(HCC)和肝硬化相关的一种较为常见的并发症,是全球公认的重大健康问题。这主要是由于这些疾病的高发病率和潜在的严重后果。我们的研究旨在进行全面的文献综述,评估 18F-FDG PET-CT 在诊断和处理 HCC 患者门静脉肿瘤血栓形成(PVTT)方面的有效性、准确性和临床意义。HCC占肝脏恶性肿瘤的80%,在全球癌症发病率中排名第四,是导致癌症相关死亡率的重要因素。大多数 HCC 患者被诊断为晚期,导致患者预后恶化。门静脉受累也是一个重要的负面因素。本综述分析了 18F-FDG PET-CT 在检测和治疗 HCC 患者 PVTT 中的应用,重点强调了最大标准化摄取值作为重要诊断和预后标志的重要性。18F-FDG PET-CT 在检测复发和指导治疗策略方面具有重要价值,尤其是在高级别 HCC 患者中,并且在区分恶性门静脉血栓和良性门静脉血栓方面起着关键作用。
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Advancements in hepatocellular carcinoma management: the role of 18F-FDG PET-CT in diagnosing portal vein tumor thrombosis.

Portal vein thrombosis, a relatively frequent complication associated with hepatocellular carcinoma (HCC) and liver cirrhosis, is recognized as a significant global health concern. This is mainly due to these conditions' high prevalence and potentially severe outcomes. The aim of our study was to conduct a comprehensive literature review to evaluate the efficacy, accuracy, and clinical implications of 18F-FDG PET-CT in diagnosing and managing portal vein tumor thrombosis (PVTT) in patients with HCC. HCC, which accounts for 80% of liver malignancies, ranks as the fourth most prevalent cancer globally and is a significant contributor to cancer-related mortality. The majority of HCC patients are diagnosed at an advanced stage, leading to a deterioration in patient outcomes. Involvement of the portal vein is also a significant negative factor. This review analyzes the application of 18F-FDG PET-CT in the detection and management of PVTT in patients with HCC, with an emphasis on the importance of the maximum standardized uptake value as an essential diagnostic and prognostic marker. 18F-FDG PET-CT is invaluable for detecting recurrence and guiding management strategies, particularly in patients with high-grade HCC, and plays a pivotal role in differentiating malignant portal vein thrombi from their benign counterparts.

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来源期刊
CiteScore
2.20
自引率
6.70%
发文量
212
审稿时长
3-8 weeks
期刊介绍: Nuclear Medicine Communications, the official journal of the British Nuclear Medicine Society, is a rapid communications journal covering nuclear medicine and molecular imaging with radionuclides, and the basic supporting sciences. As well as clinical research and commentary, manuscripts describing research on preclinical and basic sciences (radiochemistry, radiopharmacy, radiobiology, radiopharmacology, medical physics, computing and engineering, and technical and nursing professions involved in delivering nuclear medicine services) are welcomed, as the journal is intended to be of interest internationally to all members of the many medical and non-medical disciplines involved in nuclear medicine. In addition to papers reporting original studies, frankly written editorials and topical reviews are a regular feature of the journal.
期刊最新文献
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