深度学习模型在精准预测心衰患者存活率中的应用。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.3233/THC-248029
Qiaohui Zhang, Demin Xu
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引用次数: 0

摘要

背景:心力衰竭是全球健康领域的一大挑战,准确预测死亡率对于制定有效的治疗方案至关重要。在这项研究中,我们采用了深度学习的 Seq2Seq 模型,整合了 12 个患者特征。通过对连续医疗记录进行精细建模,我们成功提高了死亡率预测的准确性:本研究旨在利用 Seq2Seq 模型与患者特征相结合,精确预测心衰病例的死亡率,超越传统机器学习方法的性能:研究利用深度学习中的 Seq2Seq 模型,结合 12 个患者特征,对连续医疗记录进行复杂建模。实验设计旨在比较 Seq2Seq 与传统机器学习方法在预测死亡率方面的性能:实验结果表明,Seq2Seq 模型在预测准确性方面优于传统的机器学习方法。特征重要性分析提供了关键的患者风险因素,为制定个性化治疗方案提供了有力支持:这项研究揭示了深度学习(特别是 Seq2Seq 模型)在提高心衰病例死亡率预测精度方面的重要应用。研究结果为深度学习在医学领域的应用指明了宝贵的方向,并为未来的研究和临床实践提供了重要的启示。
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Applications of deep learning models in precision prediction of survival rates for heart failure patients.

Background: Heart failure poses a significant challenge in the global health domain, and accurate prediction of mortality is crucial for devising effective treatment plans. In this study, we employed a Seq2Seq model from deep learning, integrating 12 patient features. By finely modeling continuous medical records, we successfully enhanced the accuracy of mortality prediction.

Objective: The objective of this research was to leverage the Seq2Seq model in conjunction with patient features for precise mortality prediction in heart failure cases, surpassing the performance of traditional machine learning methods.

Methods: The study utilized a Seq2Seq model in deep learning, incorporating 12 patient features, to intricately model continuous medical records. The experimental design aimed to compare the performance of Seq2Seq with traditional machine learning methods in predicting mortality rates.

Results: The experimental results demonstrated that the Seq2Seq model outperformed conventional machine learning methods in terms of predictive accuracy. Feature importance analysis provided critical patient risk factors, offering robust support for formulating personalized treatment plans.

Conclusions: This research sheds light on the significant applications of deep learning, specifically the Seq2Seq model, in enhancing the precision of mortality prediction in heart failure cases. The findings present a valuable direction for the application of deep learning in the medical field and provide crucial insights for future research and clinical practices.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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