{"title":"基于 ESIPT 的双色探针可同时检测硫化氢和肼。","authors":"Qian Gong, Youbo Lai and Weiying Lin","doi":"10.1039/D4TB00318G","DOIUrl":null,"url":null,"abstract":"<p >Hydrogen sulfide (H<small><sub>2</sub></small>S) and hydrazine (N<small><sub>2</sub></small>H<small><sub>4</sub></small>) are toxic compounds in environmental and living systems, and hydrogen sulfide is also an important signaling molecule. However, in the absence of dual-color probes capable of detecting both H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small>, the ability to monitor the crosstalk of these substances is restricted. Herein, we developed an ESIPT-based dual-response fluorescent probe (<strong>BDM-DNP</strong>) for H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> detection <em>via</em> dually responsive sites. The <strong>BDM-DNP</strong> possessed absorbing strength in the detection of H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small>, with a large Stokes shift (156 nm for H<small><sub>2</sub></small>S and 108 nm for N<small><sub>2</sub></small>H<small><sub>4</sub></small>), high selectivity and sensitivity, and good biocompatibility. Furthermore, <strong>BDM-DNP</strong> can be utilized for the detection of hydrogen sulfide and hydrazine in actual soil, and gaseous H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> in environmental systems. Notably, <strong>BDM-DNP</strong> can detect H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> in living cells for disease diagnosis and treatment evaluation.</p>","PeriodicalId":83,"journal":{"name":"Journal of Materials Chemistry B","volume":null,"pages":null},"PeriodicalIF":6.1000,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine†\",\"authors\":\"Qian Gong, Youbo Lai and Weiying Lin\",\"doi\":\"10.1039/D4TB00318G\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Hydrogen sulfide (H<small><sub>2</sub></small>S) and hydrazine (N<small><sub>2</sub></small>H<small><sub>4</sub></small>) are toxic compounds in environmental and living systems, and hydrogen sulfide is also an important signaling molecule. However, in the absence of dual-color probes capable of detecting both H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small>, the ability to monitor the crosstalk of these substances is restricted. Herein, we developed an ESIPT-based dual-response fluorescent probe (<strong>BDM-DNP</strong>) for H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> detection <em>via</em> dually responsive sites. The <strong>BDM-DNP</strong> possessed absorbing strength in the detection of H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small>, with a large Stokes shift (156 nm for H<small><sub>2</sub></small>S and 108 nm for N<small><sub>2</sub></small>H<small><sub>4</sub></small>), high selectivity and sensitivity, and good biocompatibility. Furthermore, <strong>BDM-DNP</strong> can be utilized for the detection of hydrogen sulfide and hydrazine in actual soil, and gaseous H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> in environmental systems. Notably, <strong>BDM-DNP</strong> can detect H<small><sub>2</sub></small>S and N<small><sub>2</sub></small>H<small><sub>4</sub></small> in living cells for disease diagnosis and treatment evaluation.</p>\",\"PeriodicalId\":83,\"journal\":{\"name\":\"Journal of Materials Chemistry B\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2024-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Materials Chemistry B\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/tb/d4tb00318g\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Materials Chemistry B","FirstCategoryId":"1","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/tb/d4tb00318g","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
A dual-color ESIPT-based probe for simultaneous detection of hydrogen sulfide and hydrazine†
Hydrogen sulfide (H2S) and hydrazine (N2H4) are toxic compounds in environmental and living systems, and hydrogen sulfide is also an important signaling molecule. However, in the absence of dual-color probes capable of detecting both H2S and N2H4, the ability to monitor the crosstalk of these substances is restricted. Herein, we developed an ESIPT-based dual-response fluorescent probe (BDM-DNP) for H2S and N2H4 detection via dually responsive sites. The BDM-DNP possessed absorbing strength in the detection of H2S and N2H4, with a large Stokes shift (156 nm for H2S and 108 nm for N2H4), high selectivity and sensitivity, and good biocompatibility. Furthermore, BDM-DNP can be utilized for the detection of hydrogen sulfide and hydrazine in actual soil, and gaseous H2S and N2H4 in environmental systems. Notably, BDM-DNP can detect H2S and N2H4 in living cells for disease diagnosis and treatment evaluation.
期刊介绍:
Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive:
Antifouling coatings
Biocompatible materials
Bioelectronics
Bioimaging
Biomimetics
Biomineralisation
Bionics
Biosensors
Diagnostics
Drug delivery
Gene delivery
Immunobiology
Nanomedicine
Regenerative medicine & Tissue engineering
Scaffolds
Soft robotics
Stem cells
Therapeutic devices