固体基质中手性化合物诱导的非手性分子的手性诱导和放大作用

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-05-15 DOI:10.1093/chemle/upae097

Minori Abe, C. Kachi‐Terajima, Masahiro Toyoda, Yasushi Ohga, Takunori Harada

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引用次数: 0

摘要

为了证明固态下的手性诱导和放大作用，我们研究了通过无溶剂结晶法由(S)-或(R)-1-苯基乙胺和非手性联苯-4-羧酸制备的共晶体。我们通过圆二色性光谱、傅立叶变换红外光谱和时变密度泛函理论计算研究了共晶体的手性和光学性质，发现了其在固相中的手性诱导和放大作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Chiral induction and amplification of achiral molecules induced by chiral compounds in solid matrices

To demonstrate chiral induction and amplification in the solid state, we investigated co-crystals prepared from (S)- or (R)-1-phenylethylamine and achiral biphenyl-4-carboxylic acid by solvent-free crystallization. The chiroptical and optical properties of the co-crystals were characterized by circular dichroism spectroscopy, Fourier transform infrared spectroscopy, and time-dependent density functional theory calculations, revealing chiral induction and amplification in the solid phase.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.