释放甘露糖赤藓糖醇脂质的潜力:特性与工业应用

Joana Dias de Almeida, M. Nascimento, Petar Keković, Frederico Castelo Ferreira, N. T. Faria
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引用次数: 0

摘要

甘露糖基季戊四醇脂(MELs)是最有前途的生物表面活性剂(BS)之一,是由酵母或真菌产生的糖脂,具有良好的环保性能和与人体的高度相容性。MELs 除了作为典型的表面活性剂外,还能在临界聚集浓度(CAC)或更高时形成多种结构,降低水和其他溶液的表面张力,并在多种条件下保持稳定。此外,MELs 还具有抗菌、抗肿瘤、抗氧化和抗炎活性以及皮肤和头发修复能力,这为其在化妆品、制药、生物修复和农业等领域的应用提供了可能性。然而,与其他糖脂相比,它们的市场份额仍然较低,原因是其生产工艺欠发达,生产成本较高。本综述收集了 1993 年以来文献中提到的 MEL 的潜在应用信息。此外,它还探讨了当前为提高 MEL 的市场占有率而制定的战略,以及为鼠李糖脂和槐糖脂制定的战略。
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Unlocking the Potential of Mannosylerythritol Lipids: Properties and Industrial Applications
Mannosylerythritol lipids (MELs), one of the most promising biosurfactants (BS), are glycolipids produced by yeasts or fungi, which have great environmental performance and high compatibility with the human body. MELs, besides working as typical surfactants, can form diverse structures when at or above the critical aggregation concentration (CAC), reduce the surface tension of water and other solutions, and be stable over a wide range of conditions. Among others, MELs present antimicrobial, antitumor, antioxidant and anti-inflammatory activities and skin and hair repair capacity, which opens possibilities for their use in applications from cosmetics and pharmaceutics to bioremediation and agriculture. However, their market share is still low when compared to other glycolipids, due to their less developed production process and higher production cost. This review gathers information on the potential applications of MELs mentioned in the literature since 1993. Furthermore, it also explores the current strategies being developed to enhance the market presence of MELs, in parallel with the ones developed for rhamnolipids and sophorolipids.
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