百合叶乙醇提取物作为皮肤保湿剂的手部润肤露配方

B. Barus
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摘要

百合叶(Crinum asiaticum L.)具有抗氧化剂的生物活性,并含有苷类、黄酮类、皂苷、单宁和三萜类等化合物。本研究旨在将水仙叶提取物配制成手部身体乳液剂型,并观察其对志愿者皮肤的功效,为期 4 周。这项研究是通过实验进行的。样本取自水仙叶(Crinum asiaticum L.),然后用 96% 的乙醇浸泡提取,并用旋转蒸发仪浓缩。 水仙叶乙醇提取物的配制浓度分别为 5%、8% 和 11%。制剂评估测试包括制剂的均匀性、感官、pH 值、乳液类型、刺激性测试和保湿效果测试。结果表明,水仙叶乙醇提取物可用于制作均匀的磨碎乳液制剂,该制剂在储存 4 周内稳定,pH 值为 7.52-7.25,乳液类型为水包油型,且不会消失。任何含有水仙叶乙醇的护手霜产品都能增加皮肤水分。治疗皮肤干燥最有效的护手霜和护肤霜的成分是一种浓度为 11% 的百合叶乙醇提取物制剂,涂抹在皮肤上 1 个月内,皮肤愈合率提高了 40.35%。
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A FORMULATION OF HAND BODY LOTIO FORMULATION OF HAND BODY LOTION EXTRACT ethanol from lily leaves (Crinum asiaticum L.) AS A SKIN MOISTURIZER
Lily leaves (Crinum asiaticum L.) have bioactivity as antioxidants and contain chemical compounds such as glycosides, flavonoids, saponins, tannins and triterpenoids. This study aims to formulate daffodil leaf extract into a hand body lotion dosage form and observe the effectiveness on volunteer skin for 4 weeks. This research was conducted experimentally. Samples were taken from daffodil leaves (Crinum asiaticum L.), then extracted by maceration with 96% ethanol and concentrated using a rotary evaporator.  The ethanol extract of daffodil leaves was formulated with concentrations of 5%, 8% and 11%. The preparation evaluation test includes homogeneity, organoleptic, pH, emulsion type, irritation test, and effectiveness test of the preparation to moisturize the skin. The results showed that the ethanol extract of daffodil leaves could be used to make homogeneous grated emulsion preparations which were stable during 4 weeks of storage, pH 7.52-7.25, oil-in-water emulsion type and did not disappear. Any hand cream product that contains narcissus leaf ethanol can increase skin moisture. The composition of the most effective hand and body cream in the treatment of dry skin is a preparation with a concentration of 11% ethanol extract of lily leaves, which increases skin healing by 40.35% and is applied to the skin within 1 month.
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