在侧窦提升术中使用纤维蛋白胶与富含血小板的钛纤维蛋白的临床评估(随机对照临床试验)

Mohamed Saeed, Mohamed Shokry, Ziad Mohmoud
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摘要

背景:无移植物上颌窦提升术是为萎缩的上颌后部提供足够空间植入种植体的技术之一。血凝块可被视为骨形成的成骨移植材料,Osseo 祖细胞可在其中循环、分化并再生骨。研究目的:本研究旨在评估使用纤维蛋白胶与富含钛血小板的纤维蛋白(T-PRF)作为外侧窦增量术和同时植入种植体的唯一填充材料的临床效果。材料与方法:共分三组,每组十人:研究组 1 和研究组 2(S1 和 S2),分别使用纤维蛋白胶和 T-PRF 作为填充材料;以及阴性对照组(C)。三组患者均通过侧方截骨法进行窦底隆起,并同时植入种植体。对患者术后即刻、一周后和六个月后的疼痛、术后并发症和种植体稳定性进行临床评估。结果:无论是术后即刻还是一周后,三组患者在疼痛方面均无明显差异。在种植体稳定性方面,纤维蛋白胶组(S1)的平均种植体稳定性商数(ISQ)为 73.30 ± 4.06,T-PRF 组(S2)为 70.10 ± 2.81,而对照组(C)为 64.0 ± 6.13(P2<0.001,P3=0.015)。然而,两个研究组(S1 和 S2)之间没有发现明显差异(p1 = 0.273)。
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CLINICAL EVALUATION OF USING FIBLIN GLUE VERSUS TITANIUM PLATELET-RICH FIBRIN IN LATERAL SINUS LIFTING PROCEDURE (RANDOMIZED CONTROLLED CLINICAL TRIAL)
BACKGROUND: Graftless sinus lift is one of the techniques that provides enough room for implant placement in the atrophic posterior maxilla. Blood clots can be thought of as bone-forming osteogenic graft material to which Osseo progenitors can circulate, differentiate, and regenerate bone. AIM OF THE STUDY: This study was conducted with the aim of evaluating the clinical effectiveness of using Fibrin glue versus Titanium platelet-rich fibrin (T-PRF) as the sole filling material in lateral sinus augmentation and simultaneous implant placement. MATERIALS AND METHODS: There were three groups each made up of ten participants: Study Groups 1 and 2 (S1 and S2), which received Fibrin glue and T-PRF as filling materials, respectively; and the negative Control Group (C). In the three groups, sinus floor augmentation via the lateral osteotomy approach and simultaneous implant placement were done. The patients were evaluated clinically in terms of pain, postoperative complications, and implant stability immediately postoperatively, after one week, and six months later. RESULTS: Between the three groups under study, no significant difference regarding pain was revealed, either immediately following surgery or one week later. Regarding implant stability, there was a significant increase in the mean Implant Stability Quotient (ISQ) value between Fibrin-glue Group (S1) that was 73.30 ± 4.06, and T-PRF Group (S2) that was 70.10 ± 2.81 and the Control Group (C) that was 64.0 ± 6.13 (p2<0.001, p3=0.015, respectively). However, no significant difference was found between the two study groups (S1, and S2) (p1 = 0.273).
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