综合分析不完全脊髓损伤患者步态的规程

IF 2.3 Q3 BIOCHEMICAL RESEARCH METHODS Methods and Protocols Pub Date : 2024-05-04 DOI:10.3390/mps7030039
Emelie Butler Forslund, Minh Tat Nhat Truong, Ruoli Wang, Åke Seiger, E. Gutierrez-Farewik
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引用次数: 0

摘要

这是一份全面分析脊髓损伤(SCI)导致的不完全截瘫患者步态及其影响因素的方案。脊髓损伤是一种破坏性事件,会影响感官和运动功能。由于护理水平的提高,SCI 患者正在发生变化,越来越多的人保留了受损的活动功能。优化 SCI 后的行走功能仍然是一项挑战。为了研究影响最佳活动能力的因素,卡罗林斯卡医学院、Aleris 康复站(瑞典最大的专业神经康复中心)脊柱单元和瑞典皇家理工学院 Promobilia 运动能力实验室的临床康复、神经生理学和生物机械工程专家共同开展了一项跨专业研究项目。将连续邀请患有截瘫、行动不便的成年人参加。将对肌肉力量、敏感性和痉挛性进行评估,并对步态和亚最大收缩时的能量消耗、三维运动和肌肉功能(肌电图)进行分析。还将进行创新的计算建模和数据驱动分析,包括识别异质人群中相似运动模式的群组,以及研究复杂感觉运动功能与运动表现之间联系的分析。这些结果可能有助于优化 SCI 患者的活动功能,并从终生的角度降低步态过程中继发病症的风险。
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A Protocol for Comprehensive Analysis of Gait in Individuals with Incomplete Spinal Cord Injury
This is a protocol for comprehensive analysis of gait and affecting factors in individuals with incomplete paraplegia due to spinal cord injury (SCI). A SCI is a devastating event affecting both sensory and motor functions. Due to better care, the SCI population is changing, with a greater proportion retaining impaired ambulatory function. Optimizing ambulatory function after SCI remains challenging. To investigate factors influencing optimal ambulation, a multi-professional research project was grounded with expertise from clinical rehabilitation, neurophysiology, and biomechanical engineering from Karolinska Institutet, the Spinalis Unit at Aleris Rehab Station (Sweden’s largest center for specialized neurorehabilitation), and the Promobilia MoveAbility Lab at KTH Royal Institute of Technology. Ambulatory adults with paraplegia will be consecutively invited to participate. Muscle strength, sensitivity, and spasticity will be assessed, and energy expenditure, 3D movements, and muscle function (EMG) during gait and submaximal contractions will be analyzed. Innovative computational modeling and data-driven analyses will be performed, including the identification of clusters of similar movement patterns among the heterogeneous population and analyses that study the link between complex sensorimotor function and movement performance. These results may help optimize ambulatory function for persons with SCI and decrease the risk of secondary conditions during gait with a life-long perspective.
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来源期刊
Methods and Protocols
Methods and Protocols Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
CiteScore
3.60
自引率
0.00%
发文量
85
审稿时长
8 weeks
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