尿结晶与上尿路结石的相关性分析

IF 2.4 3区 医学 Q2 UROLOGY & NEPHROLOGY Asian Journal of Urology Pub Date : 2024-10-01 DOI:10.1016/j.ajur.2024.04.003
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引用次数: 0

摘要

方法 收集 237 名尿路结石患者的临床数据,包括尿路结石类型。分析了尿液结晶的检出率及其与结石成分的相关性。根据尿液中的草酸钙结晶,采用接收者操作特征曲线分析法确定预测结石形成风险的最佳临界值。其中,201 名患者(84.81%)的结石中含有草酸钙。在这些患者中,45.77%(92/201)的病例检测出草酸钙结晶。在不同组别的草酸钙结石中,草酸钙结晶占每组检出结晶总数的 90%以上。首次结石患者的草酸钙结晶检出率高于复发患者。结论尿液中的草酸钙结晶可预测草酸钙结石的成分,当结晶数量超过 110 个/μL 时,结石形成的风险较高。这种无创方法可为临床治疗和预防策略提供指导。
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Correlation analysis between urinary crystals and upper urinary calculi

Objective

This study aimed to analyze the correlation between urinary crystals and urinary calculi.

Methods

Clinical data, including urinary crystal types, were collected from 237 patients with urinary calculi. The detection rate of urine crystals and their correlation with stone composition were analyzed. The receiver operating characteristic curve analysis was used to determine the best cut-off value for predicting stone formation risk based on calcium oxalate crystals in urine.

Results

Calcium oxalate was the most common component in 237 patients. Among them, 201 (84.81%) patients had stones containing calcium oxalate. In these patients, calcium oxalate crystals were detected in 45.77% (92/201) of cases. In different groups of calcium oxalate stones, calcium oxalate crystals accounted for more than 90% of the total number of crystals detected in each group. The detection rate of calcium oxalate crystals was higher in first-time stone formers than in recurrent patients. The receiver operating characteristic curve analysis suggested a cut-off value of 110 crystals/μL for predicting stone formation, validated with 65 patients and 100 normal people.

Conclusion

Calcium oxalate crystals in urine can predict the composition of calcium oxalate stones and indicate a higher risk of stone formation when the number exceeds 110 crystals/μL. This non-invasive method may guide clinical treatment and prevention strategies.
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来源期刊
Asian Journal of Urology
Asian Journal of Urology UROLOGY & NEPHROLOGY-
CiteScore
4.00
自引率
3.80%
发文量
100
审稿时长
4 weeks
期刊介绍: Asian Journal of Urology (AJUR), launched in October 2014, is an international peer-reviewed Open Access journal jointly founded by Shanghai Association for Science and Technology (SAST) and Second Military Medical University (SMMU). AJUR aims to build a communication platform for international researchers to effectively share scholarly achievements. It focuses on all specialties of urology both scientifically and clinically, with article types widely covering editorials, opinions, perspectives, reviews and mini-reviews, original articles, cases reports, rapid communications, and letters, etc. Fields of particular interest to the journal including, but not limited to: • Surgical oncology • Endourology • Calculi • Female urology • Erectile dysfunction • Infertility • Pediatric urology • Renal transplantation • Reconstructive surgery • Radiology • Pathology • Neurourology.
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