{"title":"评估氰基丙烯酸酯/聚甲基丙烯酸甲酯复合物作为防止皮肤摩擦和水泡的保护剂的效果","authors":"Tengfei Wang, Wei Zhang, Jia Wang, Junjie Tan, Wei Wang, Quan Zhang, Liang Xu","doi":"10.1166/sam.2024.4697","DOIUrl":null,"url":null,"abstract":"The skin is highly susceptible to friction during labor or outdoor activities, leading to blisters, bleeding, pain, and infection. In this paper, a butyl-cyanoacrylate/polymethylmethacrylate (504/PMMA) composite was developed as a protectant to prevent skin damage caused by external\n friction. The composite could rapidly solidify on the skin surface, forming a strong polymer film. Results from a rat model showed that the 504/PMMA composite effectively prevented skin damage and that increasing the proportion of PMMA improved its anti-friction performance. Moreover, the\n material is biocompatible. In this study, we offered new options for reducing skin friction and blisters, which have potential to practical applications.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the Cyanoacrylate/Polymethylmethacrylate Complex as a Protectant to Prevent Skin Friction and Blisters\",\"authors\":\"Tengfei Wang, Wei Zhang, Jia Wang, Junjie Tan, Wei Wang, Quan Zhang, Liang Xu\",\"doi\":\"10.1166/sam.2024.4697\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The skin is highly susceptible to friction during labor or outdoor activities, leading to blisters, bleeding, pain, and infection. In this paper, a butyl-cyanoacrylate/polymethylmethacrylate (504/PMMA) composite was developed as a protectant to prevent skin damage caused by external\\n friction. The composite could rapidly solidify on the skin surface, forming a strong polymer film. Results from a rat model showed that the 504/PMMA composite effectively prevented skin damage and that increasing the proportion of PMMA improved its anti-friction performance. Moreover, the\\n material is biocompatible. In this study, we offered new options for reducing skin friction and blisters, which have potential to practical applications.\",\"PeriodicalId\":21671,\"journal\":{\"name\":\"Science of Advanced Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Science of Advanced Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1166/sam.2024.4697\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science of Advanced Materials","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1166/sam.2024.4697","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of the Cyanoacrylate/Polymethylmethacrylate Complex as a Protectant to Prevent Skin Friction and Blisters
The skin is highly susceptible to friction during labor or outdoor activities, leading to blisters, bleeding, pain, and infection. In this paper, a butyl-cyanoacrylate/polymethylmethacrylate (504/PMMA) composite was developed as a protectant to prevent skin damage caused by external
friction. The composite could rapidly solidify on the skin surface, forming a strong polymer film. Results from a rat model showed that the 504/PMMA composite effectively prevented skin damage and that increasing the proportion of PMMA improved its anti-friction performance. Moreover, the
material is biocompatible. In this study, we offered new options for reducing skin friction and blisters, which have potential to practical applications.
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