心脏肿瘤学中的健康社会决定因素

IF 12 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Jacc: Cardiooncology Pub Date : 2024-06-01 DOI:10.1016/j.jaccao.2024.02.009
Foster Osei Baah MS, PhD, RN , Sonal Sharda MHS , Kimberly Davidow MD , Sadhana Jackson MD , Daphney Kernizan DO , Joshua A. Jacobs PharmD , Yvonne Baumer PharmD, PhD , Corinna L. Schultz MD , Carissa M. Baker-Smith MD, MPH , Tiffany M. Powell-Wiley MD, MPH
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引用次数: 0

摘要

要满足对更公平的心外科肿瘤治疗的需求,就必须关注心外科肿瘤疾病预防和治疗效果方面的现有差距。这对于那些受到不利的社会健康决定因素(SDOH)影响的人群尤为重要。社会政治、经济和文化因素影响着 SDOH、癌症诊断以及与肿瘤治疗相关的心脏毒性结果之间错综复杂的关系。此外,细胞信号传导机制和基因表达的表观遗传效应将不利的 SDOH 与癌症和肿瘤治疗引起的心血管疾病相关并发症联系在一起。为了减少这些差异,需要采取多方面的策略,包括关注医疗保健的获取、政策和社区参与,以改善疾病筛查和管理。跨学科团队还必须提高文化谦逊性和能力,并利用新的医疗技术促进合作,以应对不利的 SDOH 对心血管肿瘤治疗结果的影响。
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Social Determinants of Health in Cardio-Oncology

Addressing the need for more equitable cardio-oncology care requires attention to existing disparities in cardio-oncologic disease prevention and outcomes. This is particularly important among those affected by adverse social determinants of health (SDOH). The intricate relationship of SDOH, cancer diagnosis, and outcomes from cardiotoxicities associated with oncologic therapies is influenced by sociopolitical, economic, and cultural factors. Furthermore, mechanisms in cell signaling and epigenetic effects on gene expression link adverse SDOH to cancer and the CVD-related complications of oncologic therapies. To mitigate these disparities, a multifaceted strategy is needed that includes attention to health care access, policy, and community engagement for improved disease screening and management. Interdisciplinary teams must also promote cultural humility and competency and leverage new health technology to foster collaboration in addressing the impact of adverse SDOH in cardio-oncologic outcomes.

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来源期刊
CiteScore
12.50
自引率
6.30%
发文量
106
期刊介绍: JACC: CardioOncology is a specialized journal that belongs to the esteemed Journal of the American College of Cardiology (JACC) family. Its purpose is to enhance cardiovascular care for cancer patients by publishing high-quality, innovative scientific research and sharing evidence-based knowledge. The journal aims to revolutionize the field of cardio-oncology and actively involve and educate professionals in both cardiovascular and oncology fields. It covers a wide range of topics including pre-clinical, translational, and clinical research, as well as best practices in cardio-oncology. Key areas of focus include understanding disease mechanisms, utilizing in vitro and in vivo models, exploring novel and traditional therapeutics (across Phase I-IV trials), studying epidemiology, employing precision medicine, and investigating primary and secondary prevention. Amyloidosis, cardiovascular risk factors, heart failure, and vascular disease are some examples of the disease states that are of particular interest to the journal. However, it welcomes research on other relevant conditions as well.
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