评估抗病毒药物在患有心血管疾病的艾滋病患者中的使用情况,以及如何降低这些患者的心脏事件发生率。

IF 1.3 American journal of cardiovascular disease Pub Date : 2024-04-15 eCollection Date: 2024-01-01 DOI:10.62347/OBXQ4787
Azad Mojahedi
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引用次数: 0

摘要

在全球范围内,新诊断的人类免疫缺陷病毒(HIV)感染的发病率令人担忧。尽管抗逆转录病毒疗法(ART)提高了这一患者群体的生活质量,但却增加了罹患心血管疾病(CVD)的风险。对于接受抗逆转录病毒疗法的艾滋病病毒感染者(PLWH),最近的研究表明,使用他汀类药物和阿司匹林(ASA)可以降低心血管疾病的发病率或病情发展。然而,研究表明,在艾滋病病毒感染者的治疗方案中同时使用这两种药物时可能会发生相互作用。因此,我们总结了这一系统性综述,以评估患有心血管疾病的 HIV 感染者使用抗逆转录病毒疗法的情况,以及在抗逆转录病毒疗法中添加 ASA 和他汀类药物对减少心脏不良事件的影响。
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Evaluating the use of antiviral drugs in HIV patients with cardiovascular diseases and how to reduce the incidence of cardiac events in these patients.

Globally, the incidence of newly diagnosed human immunodeficiency virus (HIV) infections is concerning. Despite enhancing the quality of life for this patient population, antiretroviral therapy (ART) is linked to an increased risk of cardiovascular disease (CVD). In people living with HIV (PLWH) undergoing ART, recent research has demonstrated that the use of statins and aspirin (ASA) can reduce the incidence or progression of CVD. However, research has demonstrated that interactions may occur when these medications are used concurrently in the treatment regimen of PLWH. Therefore, we conclude this systematic review to evaluate the use of ART in HIV individuals with CVD and also the effect of adding ASA and statins to ART for reducing the cardiac adverse events.

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American journal of cardiovascular disease
American journal of cardiovascular disease CARDIAC & CARDIOVASCULAR SYSTEMS-
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