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引用次数: 0
摘要
以前从未探讨过与普萘洛尔治疗婴儿血管瘤（IH）相关的治疗负担（BOT）。本研究采用经修订的有效问卷--治疗负担问卷和一对一半结构式访谈来评估普萘洛尔治疗 IH 的治疗负担。在 80 位护理人员中，总体负担得分非常低，为 1.2 分（满分 10 分）；访谈的主题分析将主题分为管理、监控、财务和相关异常。普萘洛尔治疗 IH 的 BOT 非常低，但可以通过提供与喂养频率和低血糖风险相关的基于年龄的风险分层、围绕睡前用药时间的实用建议以及减少生命体征监测频率来进一步降低 BOT。
The burden of treatment of propranolol for infantile hemangiomas: A mixed methods study.
The burden of treatment (BOT) related to propranolol treatment for infantile hemangiomas (IH) has never previously been explored. A modified validated questionnaire, the Treatment Burden Questionnaire, and one-on-one semi-structured interviews were used to assess the BOT for propranolol for IH. Out of 80 caregivers, the overall burden score was very low at 1.2 out of 10; thematic analysis of interviews grouped themes into administration, monitoring, financial, and associated anomalies. The BOT of propranolol for IH is very low but could be reduced further by offering age-based risk stratification related to feeding frequency and risk of hypoglycemia, pragmatic advice around timing of doses before sleep, and reducing frequency of vital sign monitoring.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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