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引用次数: 0
摘要
在全球范围内，急性心肌梗死（AMI）是导致死亡的主要原因。为了改善预后和降低死亡率，早期精确诊断对医疗护理至关重要。急性心肌梗死的诊断主要依靠传统的循环生物标记物。然而，这些标志物有很多缺点。非编码 RNA（ncRNA）占转录组的很大一部分，已被证明对许多生物过程（包括疾病的发病机制）至关重要。ncRNA 在疾病的发展过程中起着重要作用，因此可被用作生物标志物。本手稿介绍了 ncRNA 作为新的 AMI 生物标记物的最新进展。
Emerging Biomarkers of Acute Myocardial Infarction, An Overview of the Newest MicroRNAs.
Globally, acute myocardial infarction (AMI) is the leading cause of death. Early and precise diagnosis is essential for medical care to enhance prognoses and reduce mortality. The diagnosis of AMI relies primarily on conventional circulating biomarkers. However, these markers have many drawbacks. Non-coding RNAs (ncRNAs) form a significant fraction of the transcriptome and have been shown to be essential for many biological processes, including the pathogenesis of the disease. ncRNAs can be utilized as biomarkers due to their important role in the disease's development. The current manuscript describes recent progress on the role of ncRNAs as new AMI biomarkers.
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GMJ is open access, peer-reviewed journal in English and supported by Noncommunicable Diseases (NCD) Research Center of Fasa University of Medical Sciences that publishing by Salvia Medical Sciences Ltd. GMJ will consider all types of the following scientific papers for publication: - Editorial’s choice - Original Researches - Review articles - Case reports - Case series - Letter (to editors, to authors, etc) - Short communications - Medical Idea
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