登革热病毒感染者的灾难性肿瘤性急性播散性脑脊髓炎：病例报告。

IF 2.3 4区医学 Q3 NEUROSCIENCES Journal of NeuroVirology Pub Date : 2024-04-01 Epub Date: 2024-05-22 DOI:10.1007/s13365-024-01210-1

Siripong Chayanopparat, Jiraporn Jitprapaikulsan, Tatchaporn Ongphichetmetha

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摘要

肿瘤活动性脱髓鞘病变（TDL）是中枢神经系统炎症性脱髓鞘疾病中一种罕见的病变，以直径超过 2 厘米的肿瘤样病变为特征。虽然各种病因都与 TDL 有关，但只有少数病例报告记录了急性播散性脑脊髓炎（ADEM）与 TDL 同时存在。在此，我们介绍了一例女性病例，她在两周前被诊断为登革热，随后出现左侧偏瘫和脑病。她的脑磁共振成像（MRI）和临床病程均符合肿瘤活动性 ADEM 的特征。

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Catastrophic tumefactive acute disseminated encephalomyelitis in patient with dengue virus: a case report.

Tumefactive demyelinating lesions (TDL) are a rare occurrence among inflammatory demyelinating diseases of the central nervous system, distinguished by tumor-like lesions exceeding 2 cm in diameter. While various etiologies have been associated with TDL, only a limited number of case reports document the coexistence of acute disseminated encephalomyelitis (ADEM) and TDL. Here, we present the case of a female diagnosed with dengue fever two weeks prior, who subsequently developed left hemiparesis and encephalopathy. Both her brain magnetic resonance imaging (MRI) and clinical course align with the characteristics of tumefactive ADEM.

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来源期刊

Journal of NeuroVirology 医学-病毒学

CiteScore

6.60

自引率

3.10%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of NeuroVirology (JNV) provides a unique platform for the publication of high-quality basic science and clinical studies on the molecular biology and pathogenesis of viral infections of the nervous system, and for reporting on the development of novel therapeutic strategies using neurotropic viral vectors. The Journal also emphasizes publication of non-viral infections that affect the central nervous system. The Journal publishes original research articles, reviews, case reports, coverage of various scientific meetings, along with supplements and special issues on selected subjects. The Journal is currently accepting submissions of original work from the following basic and clinical research areas: Aging & Neurodegeneration, Apoptosis, CNS Signal Transduction, Emerging CNS Infections, Molecular Virology, Neural-Immune Interaction, Novel Diagnostics, Novel Therapeutics, Stem Cell Biology, Transmissable Encephalopathies/Prion, Vaccine Development, Viral Genomics, Viral Neurooncology, Viral Neurochemistry, Viral Neuroimmunology, Viral Neuropharmacology.