一名孕妇在妊娠 25 周时因严重肺脓肿而紧急接受右肺下叶切除术:病例报告。

IF 0.7 Q4 SURGERY Surgical Case Reports Pub Date : 2024-05-23 DOI:10.1186/s40792-024-01932-8
Haruaki Hino, Yuki Yasuhara, Katsutoshi Nakahata, Takahiro Utsumi, Natsumi Maru, Hiroshi Matsui, Yohei Taniguchi, Tomohito Saito, Koji Tsuta, Hidetaka Okada, Tomohiro Murakawa
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引用次数: 0

摘要

背景:肺脓肿是一种严重的感染,常见于慢性阻塞性肺病、间质性肺炎、免疫缺陷病、药物引起的免疫功能低下状态和先天性肺病患者。由于必须避免对胎儿造成不良影响以确保安全分娩,因此对患有肺脓肿的孕妇采取的治疗策略具有挑战性:一名妊娠 24 周(G2P1)的 34 岁女性患者因突发右胸痛被送入妇产科。患者无明显病史,包括先天性畸形,也无吸毒或吸烟史。实验室数据显示炎症水平较高(白细胞 12,000 个/微升,C 反应蛋白 16.0 毫克/分升),计算机断层扫描显示右下叶中部有一个巨大的肺内囊肿,并有一些积液。由于患者没有先天性肺部畸形病史,她被初步诊断为肺囊肿感染,并接受了静脉抗生素治疗。然而,感染一周多仍未缓解,入院后出现高烧。关于非产科手术中早产和胎儿流产的风险,目前还没有确切的证据。然而,为了控制抗生素难治的严重感染性肺脓肿,并获得病理诊断,同时挽救母亲和胎儿的生命,我们在获得知情同意后,选择了开胸无裂隙手法行紧急右肺下叶切除术。术后感染逐渐好转,患者于术后第 16 天出院,母体和胎儿均未出现重大并发症。虽然她后来在妊娠 29 周时经历了冠状病毒病-19,但在妊娠 40 周时顺利产下一名男婴,未出现任何并发症。病理结果显示,除了与肺梗塞有关的肺脓肿外,没有发现其他感染病原体、恶性肿瘤或先天性畸形。术后一年,母婴健康:我们经历了一例罕见的孕妇肺脓肿病例,为了控制严重感染并获得正确的病理诊断,孕妇需要紧急接受右肺下叶切除术。在产科医生和麻醉师的合作下,即使孕妇离分娩还有几个月的时间,也可以安全地对严重脓肿进行紧急肺切除术。
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Emergency right lower lobectomy for severe pulmonary abscess in a pregnant woman at the 25th week of gestation: a case report.

Background: Pulmonary abscess is a severe infection commonly seen in patients with chronic obstructive pulmonary disease, interstitial pneumonia, immune deficiency disease, drug-induced immunocompromised state, and congenital pulmonary disease. The treatment strategy in pregnant women with a pulmonary abscess is considered challenging since adverse effects on the fetus must be avoided to ensure safe delivery.

Case presentation: A 34-year-old female patient at 24 weeks of gestation (G2P1) was admitted to the Department of Obstetrics and Gynecology due to sudden right chest pain. The patient had no significant medical history, including congenital anomalies, and no history of drug addiction or smoking. Laboratory data indicated high levels of inflammation (white blood cell 12,000/µL, C-reactive protein 16.0 mg/dL), and computed tomography demonstrated a large intrapulmonary cyst located in the middle of the right lower lobe, with some fluid collection. As the patient had no medical history of congenital pulmonary anomalies, she was initially diagnosed with a pulmonary cyst infection and treated with intravenous antibiotics. However, the infection did not resolve for over a week, and a spike in fever developed after admission. There was no definitive evidence concerning the risk of preterm delivery and fetal abortion during non-obstetric surgery. However, to control the severely infected pulmonary abscess that was refractory to antibiotics and obtain a pathological diagnosis while saving the life of both the mother and fetus, we elected to perform an emergent right lower lobectomy by open thoracotomy with a fissureless maneuver after receiving informed consent. Postoperatively, the infection gradually improved, and the patient was discharged on the 16th postoperative day without any major complications in the mother or fetus. Although she later experienced coronavirus disease-19 at 29 weeks of gestation, a boy was born at 40th weeks of gestation without any complications. Pathologically, no infectious agents, malignancies, or congenital anomalies other than lung abscesses associated with the pulmonary infarction were observed. The mother and child were healthy 1 year postoperatively.

Conclusions: We experienced a rare case of a pulmonary abscess in a pregnant woman who needed an emergent right lower lobectomy to control the severe infection and obtain a correct pathological diagnosis. Under cooperation from an obstetrician and anesthesiologist, emergency pulmonary resection can be performed safely for serious abscess formation even for pregnant women who have several months left until delivery.

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