夜尿和阻塞性睡眠呼吸暂停。

IF 12.1 1区 医学 Q1 UROLOGY & NEPHROLOGY Nature Reviews Urology Pub Date : 2024-05-23 DOI:10.1038/s41585-024-00887-7
Olaf P J Vrooman, Philip E V van Kerrebroeck, Michael R van Balken, Gommert A van Koeveringe, Mohammad S Rahnama'i
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引用次数: 0

摘要

夜尿,即夜间尿急,是阻塞性睡眠呼吸暂停(OSA)患者的常见症状。持续气道正压治疗可减少部分患者的夜尿现象,但其潜在机制十分复杂,尚未完全明了。OSA 会影响自律神经系统、氧化应激和内皮损伤。此外,将多尿归因于心脏负荷过重和反应性钠尿的错误信号的普遍理论也有局限性。需要采取综合方法来处理 OSA 患者的夜尿问题,同时考虑到合并症、药物使用、饮酒和生活方式等因素。有效治疗 OSA 夜尿需要多学科合作,泌尿科医生应了解 OSA 对生理的潜在影响,并将患者转诊至睡眠中心进行进一步检查。除持续气道正压治疗外,口腔用具和手术阻塞治疗等其他干预措施也可能对某些患者有益。总之,了解 OSA 与夜尿症之间复杂的相互作用对于优化患者预后至关重要。
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Nocturia and obstructive sleep apnoea.

Nocturia, the need to urinate at night, is a common symptom in patients with obstructive sleep apnoea (OSA). Continuous positive airway pressure treatment can reduce nocturia in some patients, but the underlying mechanisms are complex and not fully understood. OSA affects the autonomic nervous system, oxidative stress and endothelial damage. Furthermore, the commonly held theory attributing polyuria to a false signal of cardiac overload and response natriuresis has limitations. A comprehensive approach to the management of nocturia in OSA, considering factors such as comorbidities, medication use, alcohol consumption and lifestyle, is needed. Effective management of nocturia in OSA requires a multidisciplinary approach, and urologists should be aware of the potential effect of OSA on physiology and refer patients for further testing at a sleep centre. In addition to continuous positive airway pressure, other interventions such as oral appliances and surgical obstruction treatment could be beneficial for some patients. Overall, understanding the complex interplay between OSA and nocturia is crucial for optimizing patient outcomes.

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来源期刊
Nature Reviews Urology
Nature Reviews Urology 医学-泌尿学与肾脏学
CiteScore
12.50
自引率
2.60%
发文量
123
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.
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