多种癌症早期检测(MCED)试验:从工作台到病床优先考虑公平性。

Health affairs scholar Pub Date : 2024-05-23 eCollection Date: 2024-05-01 DOI:10.1093/haschl/qxae039
Sarah J Miller, Jamilia R Sly, Christian Rolfo, Philip Mack, Augusto Villanueva, Melissa Mazor, Ellerie Weber, Jenny J Lin, Cardinale B Smith, Emanuela Taioli
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摘要

多种癌症早期检测(MCED)是一种基于血液的检测,旨在筛查多种癌症的信号。对 MCED 检测的潜在益处和应用进行研究的兴趣和投资与日俱增。如果证明 MCED 检测具有临床实用性,就必须确保所有人(无论其人口或社会经济背景如何)都能公平地从这些检测中受益。遗憾的是,在医疗保健创新方面,这种考虑往往被忽视,直到不公平现象出现之后。我们敦促营利性公司、科学家、临床医生、付款人和政府机构在 MCED 仍处于开发和研究阶段时就优先考虑公平问题。为了避免造成和加剧癌症不公平现象,我们提出了 MCED 的 9 项公平考虑因素。
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Multi-cancer early detection (MCED) tests: prioritizing equity from bench to bedside.

Multi-cancer early detection (MCED) tests are blood-based tests designed to screen for signals of multiple cancers. There is growing interest and investment in examining the potential benefits and applications of MCED tests. If MCED tests are shown to have clinical utility, it is important to ensure that all people-regardless of their demographic or socioeconomic background-equitably benefit from these tests. Unfortunately, with health care innovation, such considerations are often ignored until after inequities emerge. We urge for-profit companies, scientists, clinicians, payers, and government agencies to prioritize equity now-when MCEDs are still being developed and researched. In an effort to avoid creating and exacerbating cancer inequities, we propose 9 equity considerations for MCEDs.

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