从 "我们所有人 "研究计划的成人电子健康记录中识别错误的身高和体重值。

IF 4 2区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Journal of Biomedical Informatics Pub Date : 2024-05-23 DOI:10.1016/j.jbi.2024.104660
Andrew Guide , Lina Sulieman , Shawn Garbett , Robert M Cronin , Matthew Spotnitz , Karthik Natarajan , Robert J. Carroll , Paul Harris , Qingxia Chen
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引用次数: 0

摘要

引言电子健康记录(EHR)是一种有用的研究数据源,但其可用性受到测量误差的影响。本研究调查了 "我们所有人 "研究项目(All of Us)电子健康记录中成人身高和体重测量的自动错误检测算法:方法:我们开发了成人身高和体重参考图表,并根据参与者的性别进行了分层。我们的分析包括来自 150,000 名参与者的 4,076,534 次身高和 5,207,328 次体重测量结果。我们使用修正的标准偏差评分、与预期值的差异以及连续测量之间的显著变化来识别误差。我们用随机抽取的 250 名参与者中经过图表审查的身高(8092)和体重(9039)对我们的方法进行了评估,并将其与当前《我们所有人》中的清理算法进行了比较:结果:所提出的算法对全部人群中 1.4% 的身高错误和 1.5% 的体重错误进行了分类。身高的灵敏度为 90.4%(95% CI:79.0-96.8%),体重的灵敏度为 65.9%(95% CI:56.9-74.1%)。高度的精确度为 73.4 %(95 % CI:60.9-83.7 %),重量的精确度为 62.9 %(95 % CI:54.0-71.1 %)。相比之下,当前的清理算法在高度误差的灵敏度(55.8%)和精确度(16.5%)方面表现较差,而在权重误差方面精确度较高(94.0%),灵敏度较低(61.9%):我们提出的算法在检测身高误差方面的表现优于权重误差。讨论:与权重相比,我们提出的算法在检测身高错误方面更胜一筹,它可以作为当前 "我们所有人 "清理算法的重要补充,用于识别错误的身高值。
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Identifying erroneous height and weight values from adult electronic health records in the All of Us research program

Introduction

Electronic Health Records (EHR) are a useful data source for research, but their usability is hindered by measurement errors. This study investigated an automatic error detection algorithm for adult height and weight measurements in EHR for the All of Us Research Program (All of Us).

Methods

We developed reference charts for adult heights and weights that were stratified on participant sex. Our analysis included 4,076,534 height and 5,207,328 wt measurements from ∼ 150,000 participants. Errors were identified using modified standard deviation scores, differences from their expected values, and significant changes between consecutive measurements. We evaluated our method with chart-reviewed heights (8,092) and weights (9,039) from 250 randomly selected participants and compared it with the current cleaning algorithm in All of Us.

Results

The proposed algorithm classified 1.4 % of height and 1.5 % of weight errors in the full cohort. Sensitivity was 90.4 % (95 % CI: 79.0–96.8 %) for heights and 65.9 % (95 % CI: 56.9–74.1 %) for weights. Precision was 73.4 % (95 % CI: 60.9–83.7 %) for heights and 62.9 (95 % CI: 54.0–71.1 %) for weights. In comparison, the current cleaning algorithm has inferior performance in sensitivity (55.8 %) and precision (16.5 %) for height errors while having higher precision (94.0 %) and lower sensitivity (61.9 %) for weight errors.

Discussion

Our proposed algorithm outperformed in detecting height errors compared to weights. It can serve as a valuable addition to the current All of Us cleaning algorithm for identifying erroneous height values.

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来源期刊
Journal of Biomedical Informatics
Journal of Biomedical Informatics 医学-计算机:跨学科应用
CiteScore
8.90
自引率
6.70%
发文量
243
审稿时长
32 days
期刊介绍: The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.
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