通过发散选择性聚焦多头自我注意力网络预测 HAMD-17 评分的自动方法

IF 3.5 3区 医学 Q2 NEUROSCIENCES Brain Research Bulletin Pub Date : 2024-05-26 DOI:10.1016/j.brainresbull.2024.110984
Jing Qin , Zhiguang Qin , Zhen Qin , Fali Li , Yueheng Peng , Yue Zhang , Yutong Yao
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引用次数: 0

摘要

本研究介绍了发散选择性聚焦多头自我注意力网络(DSFMANet),这是一种创新的深度学习模型,用于自动预测抑郁症患者的汉密尔顿抑郁评分量表-17(HAMD-17)得分。该模型为子波段引入了多分支结构,并人为地在不同分支上配置了注意力焦点因子,从而使不同子波段的注意力分布截然不同。实验结果表明,当 DSFMANet 处理子波段数据时,其性能在均方误差 (MSE)、平均绝对误差 (MAE)、均方根误差 (RMSE) 和判定系数 (R2) 等关键指标上都超过了当前的基准。这一成功在 MSE 和 MAE 方面尤为明显,其中子波段数据的性能明显优于 MSE 和 MAE,凸显了该模型在准确预测 HAMD-17 分数方面的潜力。同时,实验还比较了模型在使用子波段数据和全波段数据时的表现,肯定了选择性聚焦注意力机制在脑电图(EEG)信号处理中的优越性。DSFMANet 在使用子波段数据时表现出更高的数据处理效率,并降低了模型的复杂性。本研究的发现强调了基于子波段分析的深度学习模型在抑郁症诊断中的应用意义。DSFMANet 模型不仅有效提高了抑郁症诊断的准确性,还为未来类似应用提供了有价值的研究方向。这种基于深度学习的自动化方法能有效确定抑郁症患者的 HAMD-17 评分,从而为临床决策提供更准确、更可靠的支持。
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An automated approach for predicting HAMD-17 scores via divergent selective focused multi-heads self-attention network

This study introduces the Divergent Selective Focused Multi-heads Self-Attention Network (DSFMANet), an innovative deep learning model devised to automatically predict Hamilton Depression Rating Scale-17 (HAMD-17) scores in patients with depression. This model introduces a multi-branch structure for sub-bands and artificially configures attention focus factors on various branches, resulting in distinct attention distributions for different sub-bands. Experimental results demonstrate that when DSFMANet processes sub-band data, its performance surpasses current benchmarks in key metrics such as mean square error (MSE), mean absolute error (MAE), root mean square error (RMSE), and coefficient of determination (R2). This success is particularly evident in terms of MSE and MAE, where the performance of sub-band data is significantly superior, highlighting the model's potential in accurately predicting HAMD-17 scores. Concurrently, the experiment also compared the model's performance with sub-band and full-band data, affirming the superiority of the selective focus attention mechanism in electroencephalography (EEG) signal processing. DSFMANet, when utilizing sub-band data, exhibits higher data processing efficiency and reduced model complexity. The findings of this study underscore the significance of employing deep learning models based on sub-band analysis in depression diagnosis. The DSFMANet model not only effectively enhances the accuracy of depression diagnosis but also offers valuable research directions for similar applications in the future. This deep learning-based automated approach can effectively ascertain the HAMD-17 scores of patients with depression, thus offering more accurate and reliable support for clinical decision-making.

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来源期刊
Brain Research Bulletin
Brain Research Bulletin 医学-神经科学
CiteScore
6.90
自引率
2.60%
发文量
253
审稿时长
67 days
期刊介绍: The Brain Research Bulletin (BRB) aims to publish novel work that advances our knowledge of molecular and cellular mechanisms that underlie neural network properties associated with behavior, cognition and other brain functions during neurodevelopment and in the adult. Although clinical research is out of the Journal''s scope, the BRB also aims to publish translation research that provides insight into biological mechanisms and processes associated with neurodegeneration mechanisms, neurological diseases and neuropsychiatric disorders. The Journal is especially interested in research using novel methodologies, such as optogenetics, multielectrode array recordings and life imaging in wild-type and genetically-modified animal models, with the goal to advance our understanding of how neurons, glia and networks function in vivo.
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