Hyperemesis Gravidarum: Associations With Personal and Family History of Nausea

(Acta Obstet Gynecol Scand. 2023;102:1176–1182) Nausea and vomiting are prevalent in early pregnancy, with 3.6% experiencing severe symptoms termed hyperemesis gravidarum (HG). Characterized by early onset, impaired eating, and impactful daily life restrictions, HG leads to dehydration and weight loss, becoming a primary cause for early pregnancy hospitalization. Unfortunately, health care recognition of HG is insufficient, resulting in underdiagnosis and undertreatment. The condition’s multifactorial origins include vestibular, olfactory, hormonal, and gastrointestinal factors. General nausea links to various situations and a family history of HG suggests a genetic component. Research indicates that women with a history of nausea may be more susceptible to HG. Identifying such connections can aid health care professionals in recognizing and managing HG risk.