人类生命诞生过程中的动能和自由能原理

Yasunari Miyagi, Y. Mio, K. Yumoto, R. Hirata, T. Habara, N. Hayashi
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引用次数: 0

摘要

这项回顾性非介入性研究调查了 18 个受精卵(7 个正常,11 个异常)的视频图像的动能,这些图像是由一个延时装置记录的,直到第一次分裂开始。通过光流法测量了细胞质颗粒的标准值。正常病例的动能有三个阶段:第 1、2 和 3 阶段分别为 2.199 × 10-24 ± 2.076 × 10-24、2.369 × 10-24 ± 1.255 × 10-24、1.078 × 10-24 ± 4.720 × 10-25 (J)。在第 2 阶段,正常和异常病例的能量分别为 2.369 × 10-24 ± 1.255 × 10-24 和 4.694 × 10-24 ± 2.996 × 10-24 (J)(平均值 ± SD,p = 0.0372),所需时间分别为 8.114 ± 2.937 和 6.018 ± 5.685 (H)(p = 0.0413)。动能变化被认为是应用自由能原理的一个条件,该原理指出,任何自组织系统要在其环境中处于平衡状态,就必须使其信息自由能最小化。在用自由能原理解释动能的同时,建议将其用于临床,这将进一步加深我们对人类生命诞生方面的受精卵发育现象的理解。
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Kinetic Energy and the Free Energy Principle in the Birth of Human Life
The retrospective noninterventional study investigated the kinetic energy of video images of 18 fertilized eggs (7 were normal and 11 were abnormal) recorded by a time-lapse device leading up to the beginning of the first cleavage. The norm values of cytoplasmic particles were measured by the optical flow method. Three phase profiles for normal cases were found regarding the kinetic energy: 2.199 × 10−24 ± 2.076 × 10−24, 2.369 × 10−24 ± 1.255 × 10−24, and 1.078 × 10−24 ± 4.720 × 10−25 (J) for phases 1, 2, and 3, respectively. In phase 2, the energies were 2.369 × 10−24 ± 1.255 × 10−24 and 4.694 × 10−24 ± 2.996 × 10−24 (J) (mean ± SD, p = 0.0372), and the time required was 8.114 ± 2.937 and 6.018 ± 5.685 (H) (p = 0.0413) for the normal and abnormal cases, respectively. The kinetic energy change was considered a condition for applying the free energy principle, which states that for any self-organized system to be in equilibrium in its environment, it must minimize its informational free energy. The kinetic energy, while interpreting it in terms of the free energy principle suggesting clinical usefulness, would further our understanding of the phenomenon of fertilized egg development with respect to the birth of human life.
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