加拿大嗜铬细胞瘤围手术期管理的差异

Linda C. Qu, A. Istl, Elaine Tang, Richard C. Chaulk, Daryl Gray
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引用次数: 1

摘要

导言:尽管最近制定了共识指南,但嗜铬细胞瘤的治疗仍存在很大差异。我们的研究旨在了解加拿大外科医生对嗜铬细胞瘤围手术期处理的现状:我们向为嗜铬细胞瘤实施肾上腺切除术的加拿大外科医生发送了一份包含 23 个项目的在线调查。我们评估了个人和机构的做法,包括术前和术后管理:全国回复率为 51.8%。来自 9 个省的外科医生做出了回应,其中大多数是普外科医生(70.4%)。在多学科肿瘤委员会审查嗜铬细胞瘤患者并非常规做法(12%),仅有 42.3% 的医生坚持让患者接受基因检测。在半数受访机构中,术前α和β受体阻滞仅由内分泌科负责(53.8%),另一半机构则采用多学科方法。半数受访者让嗜铬细胞瘤患者在手术日之前入院。术后,11.5% 的受访者会根据个人偏好或机构惯例将患者送入重症监护室进行监护。多变量分析发现,人口统计学或术前因素与围手术期管理之间没有明显关系:结论:加拿大各地外科医生对接受肾上腺切除术治疗嗜铬细胞瘤患者的围手术期管理差异很大。尽管最近出台了实践指南,但只有不到一半的受访者会例行转诊患者进行基因检测。外科医生的偏好和机构惯例是术前入院和术后常规入住重症监护室的主要驱动力,尽管缺乏证据支持这种做法。
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Variability in perioperative management of pheochromocytoma in Canada
Introduction: Despite recent consensus guidelines, there is substantial variability in the management of pheochromocytomas. Our study aimed to characterize the current state of perioperative pheochromocytoma management by Canadian surgeons. Methods: A 23-item online survey was sent to Canadian surgeons who perform adrenalectomies for pheochromocytoma. We assessed personal and institutional practices, including preoperative and postoperative management. Results: National response rate was 51.8%. Surgeons from nine provinces responded; the majority were general surgeons (70.4%). Reviewing pheochromocytoma patients at a multidisciplinary tumor board was not routine practice (12%) and only 42.3% consistently referred patients for genetic testing. Preoperative α- and β-blockade at half of the respondent institutions were performed by endocrinology alone (53.8%), with the other half employing a multidisciplinary approach. Half of respondents admitted their pheochromocytoma patients to hospital prior to the day of surgery. Postoperatively, 11.5% of respondents routinely admitted their patients to the ICU for monitoring based on personal preference or institutional convention. Multivariate analyses found no significant relationships between demographics or preoperative factors and perioperative management. Conclusions: Perioperative surgeon management of patients undergoing adrenalectomy for pheochromocytoma was highly variable across Canada. Less than half of respondents routinely refer patients for genetic testing, despite recent practice guidelines. Surgeon preference and institutional convention are the main drivers behind preoperative admission and routine postoperative ICU admission, despite a lack of evidence to support this practice.
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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
167
期刊介绍: Published by the Canadian Urological Association, the Canadian Urological Association Journal (CUAJ) released its first issue in March 2007, and was published four times that year under the guidance of founding editor (Editor Emeritus as of 2012), Dr. Laurence H. Klotz. In 2008, CUAJ became a bimonthly publication. As of 2013, articles have been published monthly, alternating between print and online-only versions (print issues are available in February, April, June, August, October, and December; online-only issues are produced in January, March, May, July, September, and November). In 2017, the journal launched an ahead-of-print publishing strategy, in which accepted manuscripts are published electronically on our website and cited on PubMed ahead of their official issue-based publication date. By significantly shortening the time to article availability, we offer our readers more flexibility in the way they engage with our content: as a continuous stream, or in a monthly “package,” or both. CUAJ covers a broad range of urological topics — oncology, pediatrics, transplantation, endourology, female urology, infertility, and more. We take pride in showcasing the work of some of Canada’s top investigators and providing our readers with the latest relevant evidence-based research, and on being the primary repository for major guidelines and other important practice recommendations. Our long-term vision is to become an essential destination for urology-based research, education, and advocacy for both physicians and patients, and to act as a springboard for discussions within the urologic community.
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