Jesslyn Park, Hetvee Desai, José Liboy-Lugo, Sohyun Gu, Ziad M. Jowhar, Albert Xu, S. Floor
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IGHMBP2 deletion suppresses translation and activates the integrated stress response
We characterized the genetic consequences of deleting IGHMBP2—a disease-relevant perturbation—in human cells. IGHMBP2-dependent gene expression changes included up-regulation of ATF4, a key ISR factor.
期刊介绍：
ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric.
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