Samantha G. Fernandez, Lucas Ferguson, Nicholas T. Ingolia
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Ribosome rescue factor PELOTA modulates translation start site choice for C/EBPα protein isoforms
Alternative translation initiation on a single mRNA can generate distinct protein isoforms. This work finds that the ribosome rescue factor, PELOTA, influences start site choice on the developmental transcription factor, C/EBPα.
期刊介绍:
Life Science Alliance is a global, open-access, editorially independent, and peer-reviewed journal launched by an alliance of EMBO Press, Rockefeller University Press, and Cold Spring Harbor Laboratory Press. Life Science Alliance is committed to rapid, fair, and transparent publication of valuable research from across all areas in the life sciences.