双中性粒细胞亚群通过 IL-1β 或 PD-L1 加重或抑制结核病的炎症反应

IF 3.3 2区生物学 Q1 BIOLOGY Life Science Alliance Pub Date : 2024-05-21 DOI:10.26508/lsa.202402623

Emilie Doz-Deblauwe, Badreddine Bounab, F. Carreras, J. Fahel, Sergio C. Oliveira, Mohamed Lamkanfi, Y. Le Vern, P. Germon, Julien Pichon, Florent Kempf, Christophe Paget, Aude Rémot, Nathalie Winter

{"title":"双中性粒细胞亚群通过 IL-1β 或 PD-L1 加重或抑制结核病的炎症反应","authors":"Emilie Doz-Deblauwe, Badreddine Bounab, F. Carreras, J. Fahel, Sergio C. Oliveira, Mohamed Lamkanfi, Y. Le Vern, P. Germon, Julien Pichon, Florent Kempf, Christophe Paget, Aude Rémot, Nathalie Winter","doi":"10.26508/lsa.202402623","DOIUrl":null,"url":null,"abstract":"Neutrophils, key cells in tuberculosis, reach the lungs as two distinct subsets playing opposite roles in inflammation: either exacerbating via IL-1b or dampening via PD-L1.","PeriodicalId":18081,"journal":{"name":"Life Science Alliance","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1\",\"authors\":\"Emilie Doz-Deblauwe, Badreddine Bounab, F. Carreras, J. Fahel, Sergio C. Oliveira, Mohamed Lamkanfi, Y. Le Vern, P. Germon, Julien Pichon, Florent Kempf, Christophe Paget, Aude Rémot, Nathalie Winter\",\"doi\":\"10.26508/lsa.202402623\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neutrophils, key cells in tuberculosis, reach the lungs as two distinct subsets playing opposite roles in inflammation: either exacerbating via IL-1b or dampening via PD-L1.\",\"PeriodicalId\":18081,\"journal\":{\"name\":\"Life Science Alliance\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Life Science Alliance\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.26508/lsa.202402623\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Life Science Alliance","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.26508/lsa.202402623","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

中性粒细胞是结核病的关键细胞，它们以两种不同的亚群形式进入肺部，在炎症中发挥着相反的作用：或者通过 IL-1b 使炎症加剧，或者通过 PD-L1 使炎症减弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1

Neutrophils, key cells in tuberculosis, reach the lungs as two distinct subsets playing opposite roles in inflammation: either exacerbating via IL-1b or dampening via PD-L1.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Life Science Alliance Agricultural and Biological Sciences-Plant Science

CiteScore

5.80

自引率

2.30%

发文量

241

审稿时长

10 weeks

期刊介绍： Life Science Alliance is a global, open-access, editorially independent, and peer-reviewed journal launched by an alliance of EMBO Press, Rockefeller University Press, and Cold Spring Harbor Laboratory Press. Life Science Alliance is committed to rapid, fair, and transparent publication of valuable research from across all areas in the life sciences.