妊娠期血栓性微血管病：目前的认识和管理策略

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY ACS Applied Materials & Interfaces Pub Date : 2024-08-01 DOI:10.1016/j.ekir.2024.05.016

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引用次数: 0

摘要

血栓性微血管病（TMA）是一组以微血管血栓形成和内脏损害为特征的异质性疾病。妊娠相关性血栓性微血管病（p-TMA）已成为一种独特的临床实体，具有独特的诊断挑战。确定 p-TMA 的具体形式对于进行适当和及时的治疗至关重要。本综述全面概述了与妊娠相关的各种形式的血栓性微血管病，重点介绍了我们目前对其病理生理学的理解以及每种病的诊断和治疗的演变情况。

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Thrombotic Microangiopathy in Pregnancy: Current Understanding and Management Strategies

Thrombotic microangiopathy (TMA) represents a heterogeneous group of disorders characterized by microvascular thrombosis and end-organ damage. Pregnancy-associated thrombotic microangiopathy (p-TMA) has emerged as a distinct clinical entity with unique diagnostic challenges. Identifying the specific form of p-TMA is critical for appropriate and timely management. This review offers a comprehensive overview of the various forms of thrombotic microangiopathies associated with pregnancy, highlighting our current understanding of their pathophysiology and the evolving landscape of diagnosis and treatment for each.

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来源期刊

ACS Applied Materials & Interfaces 工程技术-材料科学：综合

CiteScore

16.00

自引率

6.30%

发文量

4978

审稿时长

1.8 months

期刊介绍： ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.