妊娠期血栓性微血管病：目前的认识和管理策略

IF 5.7 2区医学 Q1 UROLOGY & NEPHROLOGY Kidney International Reports Pub Date : 2024-08-01 DOI:10.1016/j.ekir.2024.05.016

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引用次数: 0

摘要

血栓性微血管病（TMA）是一组以微血管血栓形成和内脏损害为特征的异质性疾病。妊娠相关性血栓性微血管病（p-TMA）已成为一种独特的临床实体，具有独特的诊断挑战。确定 p-TMA 的具体形式对于进行适当和及时的治疗至关重要。本综述全面概述了与妊娠相关的各种形式的血栓性微血管病，重点介绍了我们目前对其病理生理学的理解以及每种病的诊断和治疗的演变情况。

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Thrombotic Microangiopathy in Pregnancy: Current Understanding and Management Strategies

Thrombotic microangiopathy (TMA) represents a heterogeneous group of disorders characterized by microvascular thrombosis and end-organ damage. Pregnancy-associated thrombotic microangiopathy (p-TMA) has emerged as a distinct clinical entity with unique diagnostic challenges. Identifying the specific form of p-TMA is critical for appropriate and timely management. This review offers a comprehensive overview of the various forms of thrombotic microangiopathies associated with pregnancy, highlighting our current understanding of their pathophysiology and the evolving landscape of diagnosis and treatment for each.

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来源期刊

Kidney International Reports Medicine-Nephrology

CiteScore

7.70

自引率

3.30%

发文量

1578

审稿时长

8 weeks

期刊介绍： Kidney International Reports, an official journal of the International Society of Nephrology, is a peer-reviewed, open access journal devoted to the publication of leading research and developments related to kidney disease. With the primary aim of contributing to improved care of patients with kidney disease, the journal will publish original clinical and select translational articles and educational content related to the pathogenesis, evaluation and management of acute and chronic kidney disease, end stage renal disease (including transplantation), acid-base, fluid and electrolyte disturbances and hypertension. Of particular interest are submissions related to clinical trials, epidemiology, systematic reviews (including meta-analyses) and outcomes research. The journal will also provide a platform for wider dissemination of national and regional guidelines as well as consensus meeting reports.