降钙素基因相关肽抑制剂治疗儿童和青少年偏头痛综述

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY Pediatric neurology Pub Date : 2024-05-23 DOI:10.1016/j.pediatrneurol.2024.05.013

Lisa Moore DO , Ann Pakalnis MD

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引用次数: 0

摘要

目前针对儿科偏头痛的治疗方法中，经过充分研究的方法非常有限。降钙素基因相关肽（CGRP）抑制剂是一种安全有效的成人治疗方法，在某些临床情况下可能适用于儿童患者。我们介绍了与降钙素基因相关肽有关的偏头痛病理生理学，概述了现有的药物，并讨论了在这一人群中的临床应用。

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Calcitonin Gene-Related Peptide Inhibitors in the Treatment of Migraine in the Pediatric and Adolescent Populations: A Review

There are limited well-studied treatments for migraine in the pediatric population. Calcitonin gene-related peptide (CGRP) inhibitors are an established safe and effective treatment in adults, and use may be appropriate for pediatric patients in certain clinical situations. We describe migraine pathophysiology as it relates to CGRP, provide an overview of available medications, and discuss clinical usage in this population.

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来源期刊

Pediatric neurology 医学-临床神经学

CiteScore

4.80

自引率

2.60%

发文量

176

审稿时长

78 days

期刊介绍： Pediatric Neurology publishes timely peer-reviewed clinical and research articles covering all aspects of the developing nervous system. Pediatric Neurology features up-to-the-minute publication of the latest advances in the diagnosis, management, and treatment of pediatric neurologic disorders. The journal''s editor, E. Steve Roach, in conjunction with the team of Associate Editors, heads an internationally recognized editorial board, ensuring the most authoritative and extensive coverage of the field. Among the topics covered are: epilepsy, mitochondrial diseases, congenital malformations, chromosomopathies, peripheral neuropathies, perinatal and childhood stroke, cerebral palsy, as well as other diseases affecting the developing nervous system.